Episodes

The 'Big Mac effect:' the unhealthy combination of refined carbohydrates and saturated fat

Posted on April 6th 2022 (about 2 years)
Views: 2546

In this clip, Ronald Krauss discusses the negative combinative effect of consuming added sugars and saturated fat together.

High intake of carbohydrates linked with all cause mortality | Eric Verdin

Posted on July 15th 2019 (almost 5 years)
Views: 2540

Dr. Eric Verdin explains the importance of the insulin signaling pathway in aging and highlights both animal and human research in this area.

Why late-night eating disrupts glucose metabolism | Dr. Satchin Panda

Posted on July 27th 2021 (over 2 years)
Views: 2541

In this clip, Dr. Satchin Panda describes the relationship between melatonin and insulin and how this might determine the best time to eat.

Ketones may preserve muscle mass during fasting | Dr. Dominic D'Agostino

Posted on May 21st 2022 (almost 2 years)
Views: 2528

In this clip, Dr. Dominic D'Agostino discusses how ketones produced during fasting and ketosis protect against muscle loss.

Telomerase repairs telomeres and prevents senescence, but is hijacked by 80 to 90% of cancers

Posted on June 25th 2019 (almost 5 years)
Views: 2512

Dr. Elissa Epel discusses how cancer cells exploit the regenerative capacity of telomerase to perpetually divide, essentially becoming immortal.

Deprivation of nutrients (starvation) and other signals that play a key role in inducing autophagy

Posted on July 15th 2019 (almost 5 years)
Views: 2499

Dr. Guido Kroemer discusses changes that occur within cells that signal the need to induce autophagy.

Sulforaphane’s effect on urinary health | Jed Fahey

Posted on January 27th 2020 (about 4 years)
Views: 2489

Dr. Fahey describes the metabolic fate of sulforaphane and the current state of research on its effects against bladder cancer.

Do healthy people benefit from intermittent fasting? | Dr. Mark Mattson

Posted on April 2nd 2022 (about 2 years)
Views: 2468

In this clip, Dr. Mark Mattson predicts that intermittent fasting benefits both overweight and healthy weight people.

Rhonda Patrick discusses sauna use associated with lowering risk for dementia and heart disease

Posted on July 15th 2019 (almost 5 years)
Views: 2466

Dr. Rhonda Patrick describes the role that heat shock proteins play in reducing the risk of disease.

What is Dr Phillips doing to age well? | Dr. Stuart Phillips

Posted on July 12th 2022 (almost 2 years)
Views: 2466

In this clip, Dr. Stuart Phillips describes his current lifestyle to optimize health and longevity.

Reduction of inflammation from sulforaphane supplementation as a treatment for depression | Jed Fahey

Posted on January 27th 2020 (about 4 years)
Views: 2464

Dr. Jed Fahey discusses the potential therapeutic benefit of sulforaphane in treating depression.

Methyltransferases and TET, a demethylation enzyme, alter epigenetic age | Steve Horvath

Posted on December 31st 2020 (over 3 years)
Views: 2454

Methylation and demethylation are critical processes in development and interfering with the enzymes that carry out these two opposing processes can play critical roles in epigenetic age.

Break habits like overeating and smoking with mindfulness | Ashley Mason, Ph.D.

Posted on April 2nd 2022 (about 2 years)
Views: 2452

In this clip, Dr. Ashley Mason describes how mindfulness, a cognitive behavioral strategy, can help mitigate harmful behaviors like overeating and smoking.

"Type 3 diabetes" — could blood-brain barrier breakdown be the cause? | Axel Montagne, Ph.D.

Posted on March 25th 2023 (about 1 year)
Views: 2448

In this clip, Dr. Axel Montagne highlights the blood-brain barrier changes that potentially contribute to Alzheimer's disease.

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