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Time-restricted eating and longer daily fasting times improved health and longevity independent of calories or diet composition in male mice.
It is much more challenging to study the effects of time-restricted eating on longevity in humans but other biomarkers of health have been measured. For example, time-restricted eating within a 6-hour window without reducing calories or losing weight improves insulin sensitivity, beta cell function, blood pressure, oxidative stress and reduces evening appetite.
Dr. Satchin Panda has discussed many benefits of time-restricted eating a couple of times on my podcast. You can check those out on the episode page.
I would like to know the benefit correlation between mice and humans. If this diet allows a mouse to live 20% longer could this help a human live 10% longer.
Agreed. Keep in mind that a 48 hour fast in mice results in a 20% reduction in body weight whereas it results in a 1-2% reduction in body weight in humans. Perhaps a stricter TRE plus prolonged fasting in humans may move the needle a little more…