@jwilson13 What would be interesting is the flip side of this: what is responsible for the negative regulation of BMAL-1? If chronic inflammatory diseases like arthritis have over active macrophages due to BMAL-1 expression, can we reverse that by activating a negative regulator of it?
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@jwilson13 What would be interesting is the flip side of this: what is responsible for the negative regulation of BMAL-1? If chronic inflammatory diseases like arthritis have over active macrophages due to BMAL-1 expression, can we reverse that by activating a negative regulator of it?