From the article:
Quan’s work identified hyaluronic acid as the key signal released by endothelial cells to stimulate microglia and promote oxidative damage. “To prevent the inflammation from being intensified in the brain, you have to stop the communication between the two cell types” […] “We found ascorbyl palmitate, also known as ‘Vitamin C Ester,’ to be quite effective in inhibiting microglia and reducing the production of inflammatory hyaluronic acid.”