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This suggests that chronic enhancement of pro-inflammatory mediators really is not just a bystander but an actual driver of aging. These data are in line with a recent study in exceptionally old populations (from 90-110+ years old) that identified low inflammation was the only predictor of survival and cognitive function (aside from age itself). In my opinion, this implies that we should try and attempt to mitigate inflammation in order to live a long and healthy life.

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