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From the article:

The study population had 891 middle-aged men, with an average age of 54 years. The men were randomly assigned to receive one of three treatments: 293 men to lifestyle modification, 305 to the diabetes drug metformin and 293 to inactive placebo pills. Lifestyle modifications consisted of exercising for 150 minutes a week and eating less fat and fewer calories.

The results showed that low testosterone levels are common in overweight men with prediabetes, Hayes said. At the beginning of the study, nearly one in four men had low testosterone levels, considered to be below 300 nanograms per deciliter.

With lifestyle modification, the prevalence of low testosterone levels decreased from about 20 percent to 11 percent after one year, a 46 percent decrease, the authors reported. The prevalence of low testosterone was unchanged in the metformin group (24.8 versus 23.8 percent) and the placebo group (25.6 versus 24.6 percent).

Men in the lifestyle modification group lost an average of about 17 pounds (7.8 kilograms) over the one-year study, according to the abstract. The increase in testosterone levels in that group correlated with decreasing body weight and waist size.

“Losing weight not only reduces the risk of prediabetic men progressing to diabetes but also appears to increase their body’s production of testosterone,” Hayes said.

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