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New data suggests the human heart evolved to endure regular bouts of sustained moderate-intensity endurance exercise and appears partly dependent upon it. Lack of endurance activity changes the shape of the human heart to reflect more of a chimplike heart.
This new data suggests that the human heart appears partly dependent upon moderate endurance exercise and its absence, in combination with a bad diet, likely contributes to hypertensive heart disease.
Link to the full study: https://www.pnas.org/content/early/2019/09/10/1906902116