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From the article:

The “amazing” result was that the mice that both received chemotherapy and exercised had significantly smaller tumors after two weeks than mice that only received doxorubicin.

Further studies will investigate exactly how exercise enhances the effect of doxorubicin, but the Penn team believes it could be in part because exercise increases blood flow to the tumor, bringing with it more of the drug in the bloodstream.

Aerobic exercise improves blood flow to tumors by remodeling abnormal blood vessels, which may improve the penetration of drugs and ultimately be partly responsible for these effects.

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