Parenthood reshapes daily life in ways that could influence brain health and aging, yet its long-term effects are largely unknown. A study examined whether the number of children people had was linked to differences in cognitive performance and brain age in both women and men. Researchers included 303,196 UK Biobank participants of European ancestry who had no diagnosed brain or nervous-system disorders. The sample comprised 160,077 women, with an average age of 56.7 years, and 143,119 men, with an average age of 57.5 years. Participants were grouped according to whether they had no children, ... aging brain cognition pregnancy
Read moreSleep problems are common among people with diabetes and place an additional burden on daily life. Because minerals play important roles in sleep regulation and disrupted mineral levels are common in diabetes, researchers examined whether magnesium and potassium could improve sleep in people with diabetes and insomnia. In this study, 320 participants were assigned to placebo tablets, magnesium gluconate tablets (2 x 250 mg), potassium chloride tablets (2 x 250 mg), or one magnesium plus one potassium tablet for 2 months. Researchers assessed insomnia using the Insomnia Severity Index, a quest... diabetes magnesium sleep
Read morePolycystic ovary syndrome (PCOS) affects about 1 in 5 women of reproductive age and is often difficult to treat, particularly when it comes to weight loss and hormone balance. In a new randomized trial, researchers tested whether time-restricted eating (TRE) could improve body weight and metabolic health in PCOS patients without requiring calorie counting. The study included 76 overweight or obese women aged 18 to 45 with PCOS. For 6 months, one group ate only between 1 p.m. and 7 p.m., one group followed a diet meant to reduce daily calorie intake by 25%, and a control group kept its usual d... hormones insulin resistance metabolism time-restricted eating
Read moreSilicone bakeware has become a kitchen staple for its flexibility and nonstick surface, yet little is known about how much of its chemical ingredients migrate into food or the air when heated. Scientists at Health Canada set out to fill that gap by measuring how cyclic siloxanes, chemical compounds that can remain as residual substances in silicone baking forms after the manufacturing process, behave during typical baking conditions. The team tested 25 new silicone baking products bought in Canada, including cupcake molds, loaf containers, and cookie sheets. Each was baked at 177°C (338°F) fo... pollution environment
Read more[toc position='left'] Consider a drug capable of reversing the effects of aging on the heart, restoring its youthful function. That's what researchers observed when they gave dogs rapamycin—a drug traditionally used to treat certain cancers and prevent organ transplant rejection. The findings were striking: The dogs exhibited marked improvements in heart function, effectively reversing the age-related changes typically seen in aging. While these findings are remarkable, they add to a growing body of research indicating that rapamycin might enhance healthspan and promote longevity in various sp... aging autophagy metabolism immune system cancer drug
Read more[toc position='left'] Introduction Magnesium is an essential dietary mineral. It plays critical roles in myriad physiological processes, serving as a cofactor to more than 300 enzymes in the human body and maintaining the integrity of cellular structures and DNA. Magnesium deficiency is widespread, affecting more than half of people in the U.S. and increasing the risk of many chronic conditions, including cancer, metabolic disorders, and neurodegenerative diseases. At a glance, magnesium participates in: Enzymatic reactions, serving as a cofactor for more than 300 enzymes involved in variou... magnesium brain nutrition supplements micronutrients
Read moreBerries are a colorful and nutritious food containing many types of bioactive compounds, including anthocyanins, a type of polyphenol with blue/purple pigment. Anthocyanins from berries such as blueberries, black raspberries, chokeberries, and bilberries are recognized for their ability to protect against cardiovascular and neurodegenerative diseases (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504512/). Findings of a recent systematic review provide robust evidence demonstrating the beneficial effects of anthocyanins on cognitive performance and cardiovascular disease risk factors. Cognitiv... nutrition brain heart disease polyphenol
Read moreThe pain relieving drug acetaminophen (commonly known as Tylenol or paracetamol) is considered safe for use during pregnancy by the Food and Drug Administration and European Medicines Authority; however, recent evidence suggests that acetaminophen may increase the risk of fetal neurodevelopmental (https://pubmed.ncbi.nlm.nih.gov/29341895/), reproductive, and urogenital disorders. (https://pubmed.ncbi.nlm.nih.gov/27150289/). A group of expert scientists, clinicians, and public health professionals recently issued a statement calling for greater caution in recommending acetaminophen use during p... pregnancy autism
Read more[toc position='left'] Salmon roe – sometimes referred to as "salmon caviar" – is the internal egg mass found in female salmon. It is served in a variety of dishes, including sushi and pasta, or as a garnish or condiment to seafood or eggs. Salmon roe is rich in protein, vitamins, astaxanthin, and the omega-3 fatty acids eicosapentaenoic acid, or EPA, and docosahexaenoic acid, or DHA. Omega-3 fatty acids are long-chain polyunsaturated fatty acids. They are considered essential fatty acids because the human body cannot make them. Alpha-linolenic acid, or ALA, an omega-3 fatty acid that serves a... brain aging omega-3 diet mental health dementia alzheimer's
Read more[toc position='left'] Sirtuins are highly conserved enzymes that play key roles in healthspan and longevity in multiple organisms. They are linked to the regulation of a variety of metabolic processes, including the release of insulin, mobilization of lipids, response to stress, and modulation of lifespan.[ref doi='10.1016/j.tem.2013.12.001'] [ref doi='10.1016/j.bbapap.2009.11.021'] Sirtuins have been implicated in the pathophysiology of metabolic disorders such as type 2 diabetes; neurological disorders such as Parkinson’s disease; and many other conditions related to aging.[ref doi='10.3389/... aging heart disease circadian rhythm brain cancer inflammation fasting resveratrol
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