Muscles often remain weaker for days after intense exercise, and researchers are working to understand the biological signals that shape recovery. A new study tested whether fish oil could improve strength recovery and alter levels of specific fat-derived signaling molecules called oxylipins in the blood after a controlled bout of strenuous exercise. The study included 18 healthy men who were not doing regular lower-body strength training. Participants were randomly assigned to receive either fish oil or a placebo for eight weeks. The fish oil provided 2.5 grams per day of docosahexaenoic aci... exercise omega-3
Read moreChemotherapy often causes problems with memory, concentration, and mental fatigue, but clinics still do not have a standard way to treat these symptoms. In a large new trial, researchers tested whether a simple at-home exercise plan could help protect cognitive function during treatment and support healthy immune activity among cancer patients. The phase 3 trial included 687 adults who were starting chemotherapy at 20 oncology clinics across the United States. Participants were randomly assigned to usual care or to EXCAP, a six-week home program that combined walking with resistance-band exer... cancer exercise
Read moreCaffeine is a widely consumed psychoactive substance, but its long-term metabolic effects are often hard to isolate because coffee, tea, and soft drink habits correlate with many other health-related behaviors. To address that problem, researchers used human genetics to ask whether long-term differences in blood caffeine levels relate to adiposity and cardiometabolic disease. The researchers applied a method called Mendelian randomization, which uses naturally occurring genetic differences to explore cause-and-effect relationships. Because inherited genetic variants are fixed at conception, t... caffeine coffee metabolism
Read moreFrom the article: If smoking women with high systolic blood pressure values have 20 times higher rate of these brain bleeds than never-smoking men with low blood pressure values, it may very well be that these women diagnosed with unruptured intracranial aneurysms should be treated. On the other hand, never-smoking men with low blood pressure values and intracranial aneurysms may not need to be treated at all. In this largest SAH risk factor study ever, the study group also identified three new risk factors for SAH: previous myocardial infarction, history of stroke in mother, and elevated cho... heart disease cholesterol tobacco blood pressure stroke aneurysm
Read moreMedium-chain triglycerides improve cognitive function in Alzheimer's disease. The brain relies heavily on glucose as its primary fuel, burning as much as 130 grams of glucose per day. However, glucose metabolism in the brain is impaired in Alzheimer's disease, contributing to many of the disease's symptoms (https://link.springer.com/article/10.1007/BF03159971). Findings from a recent study demonstrate that ketones derived from medium chain triglyceride metabolism may provide an alternative fuel source for the brain in the setting of Alzheimer's disease. Ketones are molecules produced by the... brain alzheimer's neurodegeneration
Read moreFrom the article: > "We have shown that interval training does not have to be 'all out' in order to be effective," says Professor Martin Gibala. "Doing 10 one-minute sprints on a standard stationary bike with about one minute of rest in between, three times a week, works as well in improving muscle as many hours of conventional long-term biking less strenuously." > HIT means doing a number of short bursts of intense exercise with short recovery breaks in between. The authors have already shown with young healthy college students that this produces the same physical benefits as convention... exercise aerobic
Read moreDr. George Brooks discusses the metabolic pathway known as the “lactate shuttle" and its role in the recovery from traumatic brain injury. ... brain nutrition exercise parkinson's metabolism nootropics performance mitochondria lactate
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