Poor strength and muscle mass are linked with many disease states, including obesity, diabetes, and chronic inflammation. A new study in mice shows that vitamin D is critical in building and maintaining muscle. Mice with higher vitamin D levels had greater strength and muscle mass and less fat mass than those with lower levels. Researchers fed mice three different diets over a period of 12 weeks to induce deficient, normal, and high blood concentrations of vitamin D. They measured the animals' strength and body composition before and after each dietary intervention. They also measured levels ... vitamin d obesity muscle
Read moreCancer is the second leading cause of death worldwide, claiming the lives of nearly 10 million each year. As the number of cancer drugs has increased in recent years, so too have the costs associated with their use. Findings in a recent report indicate that vitamin D may reduce the number of cancer deaths, saving thousands of dollars. The authors of the study drew on data regarding age- and sex-specific cancer deaths in the German Center for Cancer Registry. They estimated the costs of cancer treatment and years of living lost in people over the age of 50 years since most cancer deaths occur ... vitamin d cancer
Read morePatients with melanoma who received immunotherapy drugs were 65% less likely to develop colitis if they also supplemented with vitamin D. These findings were validated in another group of 169 patients, which found that vitamin D supplementation lowered the chances of developing colitis by 54%. These data suggest that larger randomized controlled trials are warranted to investigate the protective effects of vitamin D on the side effects associated with immunotherapy cancer drugs. ... vitamin d cancer
Read moreFrom the article: > Researchers at the University of Notre Dame studied the correlation between bedtime regularity and resting heart rate (RHR) and found that individuals going to bed even 30 minutes later than their usual bedtime presented a significantly higher resting heart rate that lasted into the following day. [...] Surprisingly, going to bed earlier than one’s standard bedtime also showed signs of increasing RHR, though it depended on just how early. Going to bed 30 minutes earlier than usual appeared to have little effect, while going to bed more than a half hour earlier significan... sleep heart disease circadian rhythm
Read moreA supplement containing the active form of vitamin D was shown to prevent autistic-like behaviors in mice that are predisposed to them. The active vitamin D was given to pregnant mice during the first trimester and this prevented deficits in social interaction, basic learning, and stereotyped behaviors. While this study did not find a mechanism, I published a study in 2014 suggesting that low maternal vitamin D may increase the risk of autism because vitamin D controls the production of serotonin. Serotonin acts as a brain morphogen during early brain development and it shapes the structure an... vitamin d serotonin autism vitamin a
Read moreI've talked previously about what I've referred to as the sweet spot: 40-60 ng/ml. Some studies have shown that the lowest all-cause mortality happens in that range. The upper range may be important because vitamin D can be toxic at very ranges. ... vitamin d cancer aging vitamin a
Read moreProstate inflammation plays a major role in prostate cancer. Vitamin D is a hormone that regulates nearly 5% of the human genome and activates anti-inflammatory genes. 32 studies from January 1966 to January 2013 with more than 500,000 participants found that vitamin D blood levels between 40-60 ng/ml were associated with the lowest all-cause mortality. You can listen to my podcast on vitamin D to learn more about how I decide how much vitamin D to supplement with, what happens if you get too much vitamin D, the difference in vitamin D made from the sun versus a supplement, what form of vitami... vitamin d cancer inflammation vitamin a
Read moreEvery 5 ng/ml increase in blood vitamin D was associated with a 1% decrease in inflammatory T cells. Note: 10,400 IU is actually a pretty high dose of Vitamin D! Many of these people were severely deficient to start with. In fact, MS has been linked to genetically low vitamin D...meaning a gene that converts vitamin D into active vitamin D hormone does not work well in many MS patients so they need an unusually high dose of vitamin D. While an ideal dose of Vitamin D may be hard to pin down because of individual variation, what IS known is a generally ideal level. Most studies seem to show a r... vitamin d inflammation immune system vitamin a
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