Supplements are widely used by people hoping to slow aging, but most have little human evidence linking them to biological age measures. To identify which products might warrant more rigorous testing, researchers examined whether their use was associated with epigenetic age (a DNA-based estimate of biological age) in a large group of health-focused adults. The study analyzed 4,260 adults who had taken at least one saliva test for epigenetic age and provided information on their supplement use, medication use, and health-related factors. Among participants with complete questionnaire data, the... epigenetics supplements
Read moreThe immune system plays important, and sometimes surprising, roles in brain health. A new study in mice found that blocking components of the antiviral immune response may make the brain more resilient to the effects of abnormal tau – potentially preventing Alzheimer's disease and other forms of dementia. Tau is a protein found in the brain. Abnormal tau can form aggregates called tau tangles – one of the defining characteristics of Alzheimer’s disease – activating antiviral response pathways and interfering with normal brain function and cognition. Researchers studied the effects of expos... alzheimer's aging immune system virus
Read moreCellular DNA is subject to tens of thousands of injuries each day that arise from both endogenous sources, such as free radicals produced during normal metabolism, and exogenous sources, such as cytotoxic drugs, ionizing radiation, and cigarette smoke, among others. DNA damage induces genomic instability, a hallmark of aging (https://www.foundmyfitness.com/topics/hallmarks-of-aging). Evidence from a 2020 study suggests that omega-3 fatty acids protect against DNA damage. The study involved 140 healthy children and adolescents (aged 9 to 13 years). Researchers assessed the children's body meas... omega-3 dna damage
Read moreVitamins and minerals are utilized by a wide array of enzymes that protect cells and DNA from damage. Zinc, in particular, is essential for maintaining DNA integrity and adequate antioxidant defenses. A new paper reviewing the work of Dr. Bruce Ames and others highlights the importance of zinc in promoting longevity and preventing chronic diseases. Zinc is a metallic mineral that is consumed in the diet from foods such as meat, shellfish, legumes, and fortified foods. Severe zinc deficiency results in growth retardation, hair loss, skin sores, and depressed immunity and is uncommon in develope... aging inflammation dna damage immune system zinc
Read moreMaintaining healthy vitamin D status may be an important, often overlooked factor in protecting against COVID-19-associated lung injury. ... covid-19 vitamin d
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