A medical procedure used to remove harmful antibodies and lipids from the blood may have an unexpected additional target: persistent environmental pollutants. A new study asked whether apheresis could lower circulating microplastics and per- and polyfluoroalkyl substances (PFAS), often called "forever chemicals." Adults already scheduled for medically indicated apheresis provided blood samples immediately before and after treatment. In 14 people, researchers measured four PFAS. A second laboratory measured a wider PFAS panel in four people. Micro- and nanoplastic-associated signals were asses... Microplastics PFAS pollution
Read moreHow muscles respond to exercise largely depends on intensity, and researchers are testing whether targeted nutrients can influence that process. A new study examined whether an olive leaf extract rich in the polyphenol oleuropein could alter muscle responses to moderate cycling or sprint interval exercise. The crossover trial included 22 healthy, physically active young men who were not following a structured training program. Participants were assigned to either moderate-intensity continuous exercise (1 hour of cycling at 50% maximal aerobic power) or sprint interval exercise (six 30-second ... exercise mitochondria muscle polyphenol supplements
Read more[toc position='left'] Introduction Magnesium is an essential dietary mineral. It plays critical roles in myriad physiological processes, serving as a cofactor to more than 300 enzymes in the human body and maintaining the integrity of cellular structures and DNA. Magnesium deficiency is widespread, affecting more than half of people in the U.S. and increasing the risk of many chronic conditions, including cancer, metabolic disorders, and neurodegenerative diseases. At a glance, magnesium participates in: Enzymatic reactions, serving as a cofactor for more than 300 enzymes involved in variou... magnesium brain nutrition supplements micronutrients
Read morePeople who carry a newly identified variant of the APOE4 gene are more than 50 percent less likely to develop Alzheimer's disease than non-carriers, a new study shows. Carriers of an APOE3 variant are more than 60 percent less likely to develop the disease. Researchers analyzed the genetic makeup of more than 544,000 people. The participants included people who had been diagnosed with Alzheimer's disease, those with a first-degree relative who had the disease, and those who were healthy. The researchers found that two rare variants reduced the participants' risk of developing Alzheimer's dise... alzheimer's genetics dementia
Read moreVitamin D protects pancreatic beta cells in type 2 diabetes. Chronic inflammation is a principal driver of many of the pathological processes that accompany type 2 diabetes, a metabolic disorder characterized by hyperglycemia (high blood glucose) and subsequent pancreatic beta cell dysfunction. Findings from a recent study suggest that vitamin D blocks activation of the NLRP3 inflammasome, preventing inflammation-driven impairment of pancreatic beta cells. The NLRP3 inflammasome is a large, intracellular complex that plays critical roles in immune function. Its activation triggers the relea... vitamin d insulin
Read moreThe loss of muscle mass and strength, known as sarcopenia, is a significant problem in aging, affecting both healthspan and quality of life. Findings from a recent study suggest that vitamin D affects muscle function through diverse metabolic pathways. Clinicians determine a person's vitamin D status by measuring 25-hydroxyvitamin D3, or 25(OH)D3 — the inactive circulating form of vitamin D. However, a new technique, high-throughput liquid chromatography-tandem mass spectrometry (LC-MS/MS), allows researchers to quantify additional vitamin D metabolites. While these other metabolites, part of ... vitamin d muscle
Read moreBreastfeeding is the biologically superior way to feed an infant. The American Academy of Pediatrics recommends exclusive breastfeeding for the first six months of an infant's life (https://pediatrics.aappublications.org/content/129/3/e827) and then continued breastfeeding while introducing age-appropriate foods until an infant is 12 months old or older. This provides the infant optimal nutrition and immunity while supporting growth and development. New research shows that components of breast milk called human milk oligosaccharides may influence infant growth and prevent obesity in early chil... pregnancy breast milk
Read moreDr. George Brooks discusses the metabolic pathway known as the “lactate shuttle" and its role in the recovery from traumatic brain injury. ... brain nutrition exercise parkinson's metabolism nootropics performance mitochondria lactate
Watch nowLow intake of chlorophyll-rich vegetables, reduced absorption, and increased excretion are primary reasons for magnesium deficiency in the U.S. ... magnesium nutrition diet micronutrients
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