Tau is a protein abundant in nerve cells, and its abnormal forms are linked to brain deterioration in Alzheimer's disease and other neurological conditions. Researchers investigated how tau affects mitochondria, the cell's energy-producing structures, and whether interrupting that interaction could protect neurons. The study combined animal models, human neurons grown from stem cells, and brain tissue collected after death from people with and without tau-related disorders, including Alzheimer's disease. In animal and cell experiments, researchers altered tau and examined whether reverse elect... alzheimer's dementia mitochondria neurodegeneration neurons
Read morePatterns of unresolved emotion can quietly shape mood, relationships, and even a person's sense of purpose. In a new study, researchers examined whether people who tend to forgive others more often experience better overall well-being over time. The study followed 207,919 adults from 23 countries. Participants reported how often they forgave others, and researchers compared those who forgave often or always with those who rarely or never did. They then examined how this tendency related to 56 different outcomes one year later, including mental health, relationships, physical health, behavior,... mental health behavior
Read moreStatins are the first line of defense against high LDL cholesterol, but increasing the dose for better results often leads to more side effects. A team of researchers wanted to know whether adding a simple fiber supplement could make a standard statin dose more effective. To find out, they analyzed data from three clinical trials that tested psyllium taken with a statin versus the same statin taken alone. The studies included 204 adults, mostly with high LDL cholesterol, who received treatment for 4 to 12 weeks. Statins used included simvastatin, atorvastatin, or lovastatin, at doses of 10 to ... cholesterol fiber
Read moreMild cognitive impairment is often a precursor to Alzheimer's disease, marking the initial stages of cognitive decline that precede more severe dementia. Evidence suggests lifestyle factors mediate the progression of mild cognitive impairment. A recent study found that intensive lifestyle modification improves cognitive and functional performance and slows disease progression in older adults with mild cognitive impairment. Researchers conducted a randomized controlled trial involving 49 participants aged 45-90 with mild cognitive impairment or early dementia due to Alzheimer's disease. Half of... exercise alzheimer's diet omega-3 probiotics stress meditation magnesium dementia supplements
Read moreDr. Levine details his research findings that show how a structured exercise regimen can reverse up to 20 years of heart aging. ... exercise aging cardiovascular
Watch nowSugar-sweetened beverage consumption in the United States has decreased in recent decades, hopefully translating into lower rates of obesity and cardiovascular disease, both associated with excess sugar consumption. Although the cardiometabolic effects of added sugars in adults have been well-documented (https://pubmed.ncbi.nlm.nih.gov/28267855/), the effects of sugar sweetened beverages on brain function, especially in children, is under-investigated. Findings of a new report show an association between sugar-sweetened beverage consumption and poorer cognitive performance in children. Executi... brain sugar blood sugar
Read moreResearchers and clinicians are growing increasingly concerned about the possibility of COVID-19 having a persistent impact on health that extends far beyond recovery from acute illness. In particular, anecdotal reports of former patients experiencing depression, "brain fog," and difficulty finding the right words in conversation even months later appear to point to a potential long-term impact on cognition. A recent large-scale study offers evidence that COVID-19 promotes long-term cognitive deficits, even among those who experience the mildest form of the disease. The study recruited a repres... brain memory covid-19
Read moreDr. Satchidananda Panda discusses circadian rhythms, the day-night cycles that drive the multifaceted activities of the human body. ... circadian rhythm exercise brain diet sleep behavior melatonin blood sugar
Watch nowCurrent dietary guidelines for people living in the United States recommend eating at least five servings of fruits and vegetables daily as part of a healthy eating pattern. Despite these recommendations, evidence indicates that most people consume far less (https://www.cdc.gov/media/releases/2017/p1116-fruit-vegetable-consumption.html). Findings from a recent study indicate that eating two servings of fruit and three servings of vegetables daily reduces the risk of premature death. Fruits and vegetables are rich in vitamins, minerals, complex carbohydrates, and dietary fiber. They also cont... nutrition micronutrients
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