Women with the highest vitamin K1 intake were nearly half as likely to require long-term hospitalization due to hip fracture compared to women with the lowest intake, a recent study shows. Those with higher vitamin K1 intake were nearly one-third less likely to experience any kind of fracture that required hospitalization. Researchers tracked hip fractures among more than 1,300 older women (70 years and older) living in Australia for about 15 years. They also assessed the women's vitamin K1 intake using food frequency questionnaires and measured their blood vitamin D concentrations. They fou... vitamin d aging vitamin k
Read moreExercise boosts mitochondrial function and promotes weight loss among people who struggle to lose weight with dieting alone. Most weight loss programs focus on reducing caloric intake. Although this strategy works for many people, a subset of people with obesity are diet-resistant – failing to lose weight even when adhering to a low-calorie diet. Findings from a new study suggest that exercise promotes weight loss in diet-resistant women by boosting mitochondrial function. Mitochondria are tiny cellular organelles that produce energy in the presence of oxygen. They are often referred to as ... exercise obesity mitochondria
Read moreDr. Dominic D'Agostino discusses how ketones affect exercise performance, reduce inflammation, and improve neurological health. ... ketosis brain cancer diet fasting immune system intestinal permeability autoimmunity ketogenic diet
Watch nowHeat shock proteins suppress amyloid-beta toxicity in the brain. Amyloid-beta is a toxic peptide that aggregates and forms plaques in the brain with age. These plaques are widely considered a hallmark of Alzheimer's disease, a progressive neurodegenerative disease that occurs with age and is the most common cause of dementia. Findings from a 2016 study suggest that heat shock proteins suppress amyloid-beta toxicity in the brain. Heat-shock proteins comprise a large, highly conserved family of proteins that are present in all cells, across many species. They play prominent roles in many cellu... brain alzheimer's heat stress sauna neurodegeneration
Read moreIn recent years, vaping, or smoking electronic cigarettes (e-cigarettes), has emerged as a popular substitute for smoking tobacco-containing cigarettes. E-cigarettes produce a vapor that may contain nicotine as well as a variety of toxic substances, including some carcinogens. Findings from a new study suggest that some compounds in e-cigarettes trigger inflammation, promoting a leaky gut. Leaky gut, otherwise known as intestinal permeability, is a condition in which gaps form between the tight junctions between the endothelial cells that line the gut. These gaps allow pathogens like bacteria... gut intestinal permeability lipopolysaccharide
Read moreOmega-3 fatty acids ameliorate olfactory losses. The sellar and parasellar regions of the brain comprise a complex anatomical area located near the pituitary gland. Tumors in these regions often require resection using endoscopic nasal procedures, which are often associated with concomitant olfactory function losses. In some patients these losses persist long after the procedure and are sometimes permanent. Findings from a new study suggest that omega-3 fatty acids ameliorate olfactory losses associated with endoscopic nasal procedures. Omega-3 fatty acids are polyunsaturated fats that play e... omega-3 covid-19
Read moreFluid intelligence – the ability to creatively solve problems without prior knowledge or learning – declines with age. Greater losses of fluid intelligence are associated with increased risk of Alzheimer's disease. Findings from a recent study suggest that dietary factors protect against fluid intelligence losses. Nutrition plays critical roles in maintaining cognitive health. Evidence indicates that adherence to dietary patterns that include fruits, vegetables, nuts, and olive oil reduces the risk of developing Alzheimer's disease (https://pubmed.ncbi.nlm.nih.gov/25681666/). People who carry... alzheimer's aging dementia
Read moreMuscle loss can occur as part of a disease process, trauma, or aging. Although exercise can prevent muscle loss, some medical conditions or physical limitations can make exercise difficult or even impossible. Findings from a new study indicate that hyperthermia may preserve or increase muscle mass and increase mitochondrial biogenesis. Hyperthermia is a state of elevated core body temperature that activates molecular mechanisms that mitigate protein damage and drive the body's in-house repair systems. Mitochondrial biogenesis is the process by which new mitochondria are made inside cells. Man... muscle sauna
Read moreSeasonal affective disorder (SAD) is a form of depression that is influenced by seasonal changes in weather and daylight. It commonly occurs in the dark, cool days of winter but can occur during other times of the year, as well. Approximately 10 percent of people worldwide experience SAD. A new study suggests that seasonal variation in the Nrf2 antioxidant pathway regulates winter depression-like behavior in fish. Nrf2 (short for nuclear factor erythroid 2-related factor 2) is a cellular protein that regulates the expression of antioxidant and stress response proteins. Nrf2 functions within a... depression sulforaphane nrf2 traditional medicine
Read moreOlive oil, the principal fat consumed in the Mediterranean diet, is widely consumed for its flavor, versatility, and health-promoting attributes. A recent study demonstrates that the monounsaturated fats (MUFAs) in olive oil may extend lifespan by switching on the activity of key cellular proteins called sirtuins. Monounsaturated fats are dietary fats found in plant foods, such as nuts, avocados, and vegetable oils, especially olive oil, which contains approximately 75 percent of the MUFA known as oleic acid. The body stores MUFAs in lipid droplets – intracellular fat storage depots that facil... aging insulin monounsaturated fat protein
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