Dr. Rhonda Patrick compares low omega-3 status with smoking and explains how the Omega-3 Index reflects long-term intake. ... nutrition diet aging biomarkers omega-3 rhonda mortality cardiovascular supplements
Watch nowA diminished or lost sense of smell is a common feature of the early stages of Alzheimer's disease and other forms of dementia. But a new study in mice that carry the APOE4 gene variant, the primary genetic risk factor for Alzheimer's disease, shows that DHA – a type of omega-3 fatty acid found in fish – protects against these losses. APOE4-carrying mice that ate a DHA-rich diet retained their sense of smell and the ability to distinguish between objects based on their scent. Researchers fed normal mice and APOE4 carriers a regular diet or one supplemented with DHA. Then, using MRI scans, the... brain alzheimer's aging omega-3 memory genetics
Read moreThe Omega-3 Index, a biomarker developed by Drs. Bill Harris and Clemens von Schacky, measures the amount of EPA + DHA as a percentage of total fatty acids in red blood cell membranes.[ref doi='10.1016/j.ypmed.2004.02.030'] The Omega-3 Index has been proposed as a measurable biomarker of sudden cardiac death risk.[ref doi='10.1016/j.ypmed.2004.02.030'] and may provide a means of standardizing methodologies that produce equivalent measures in clinical trials, allowing researchers to interpret clinical trial outcomes more accurately.[ref doi='10.1017/S0029665120006989'] Since its inception in 20... omega-3 heart disease blood test brain mortality biomarkers
Read moreA new study shows that premature infants who received supplemental DHA, a type of omega-3 fatty acid, at birth performed better on intelligence tests later in childhood than those who did not receive DHA. This was true regardless of whether the infants were fed breast milk, formula, or both. Researchers monitored the cognitive performance of more than 650 children born before 29 weeks' gestation. From birth until roughly the age of 36 weeks' gestation, about half of the children received DHA (60 milligrams per kilogram of body weight per day) via tube feeding, while the other half did not. Whe... omega-3 development
Read moreHigher DHA concentrations cut Alzheimer's disease risk by half. Docosahexaenoic acid (DHA) is an omega-3 fatty acid found in krill oil and the meat and roe of salmon, flying fish, and pollock. When consumed in the diet (or obtained from dietary supplements), DHA preferentially accumulates in the human brain (https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.201801412R), where it plays essential roles in normal brain function. Findings from a recent study suggest that higher concentrations of DHA in red blood cells protect against Alzheimer's disease. The concentration of omega-3 fatty... alzheimer's omega-3
Read moreImpaired transport of DHA disrupts the blood-brain barrier. Lipid rafts – cholesterol-filled “bubbles” found in the cell membrane – serve as staging areas for many cellular activities. One type of lipid raft, called caveolae, facilitates the transport of substances across the membrane of endothelial cells. Findings from a 2017 study demonstrate that suppression of caveolae-mediated transport in brain endothelial cells protects the integrity of the blood-brain barrier. The blood-brain barrier is a highly selective semi-permeable barrier made up of endothelial cells connected via tight junctio... brain cancer aging omega-3 blood-brain barrier
Read moreDr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session. ... rhonda vitamin d exercise parkinson's epigenetics omega-3 fasting melatonin vaccine resveratrol sauna insulin covid-19 cardiovascular autoimmunity Hair
Watch nowDr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session. ... rhonda exercise gut microbiome sleep heart disease diabetes omega-3 fasting pregnancy melatonin vaccine iron gluten covid-19 breast milk wearable technology
Watch nowSaturated fatty acid intake induces inflammation in the hypothalamus that can eventually lead to apoptosis of hypothalamic neurons and subsequent loss of the control of caloric intake and energy expenditure. The overall health of hypothalamic neurons requires their regular renewal, a process known as neurogenesis, which is impaired in obesity (https://www.jci.org/articles/view/43134). Findings from a 2016 study showed that docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), increased hypothalamic neurogenesis in mice. DHA is an omega-3 fatty acid found in the human brain ... brain obesity omega-3 bdnf
Read moreDr. Bruce Ames discusses the CHORI Bar, a micronutrient- and fiber-dense nutrition bar developed in the Ames laboratory to manage obesity. ... obesity nutrition aging heart disease insulin resistance cholesterol inflammation magnesium vitamin k selenium
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