Physical activity is often a fundamental component of weight management strategies. However, some people experience weight loss with physical activity while others do not. A recent study found that differences in the gut microbiome influence the body's metabolic response to physical activity. The study involved 307 healthy men and 209 healthy women enrolled in two long-term cohort studies. Researchers analyzed the participants' gut microbial makeup and assessed their physical activity levels over several years. They found that a specific gut microbe called Alistipes putredinis played a cruci... exercise microbiome weight loss
Read moreCurrently selected for this coming member's digest (/crowdsponsor) by team member Melisa B. From the article: > Researchers report in the April issue of Cancer Research that the GPR109A receptor is activated by butyrate, a metabolite produced by fiber-eating bacteria in the colon. The receptor puts a double-whammy on cancer by sending signals that trigger cell death, or apoptosis, and shutting down a protein that causes inflammation, a precursor to cancer. [...] > That got the German research team to search for alternative activators of the receptor, resulting in identification of beta-... nutrition cancer diet ketosis fiber butyrate hdac inhibitor
Read more[toc position='left'] Creatine is a naturally occurring compound that is critical in storing and releasing cellular energy. It also participates in many biological processes driving pregnancy outcomes, maintaining bone mineral density and muscle mass in older adults, improving neurological function, and aiding the immune system to fight cancer. Creatine is best known for its widespread use as a dietary supplement to enhance physical performance. Creatine uptake, synthesis, storage, and supplementation Creatine uptake Creatine can be supplied exogenously (from dietary or supplemental sources) ... metabolism neurodegeneration nutrition brain aging depression pregnancy
Read moreObesity is a growing problem worldwide, especially among children and young adults. Many factors contribute to obesity, including environmental exposures (https://www.ncbi.nlm.nih.gov/pubmed/27288829), which can drive epigenetic changes. Findings from a new study suggest that maternal exposure to parabens may increase the risk of obesity among children. Parabens are widely used synthetic compounds that exert antibacterial and antifungal properties. They are commonly used in cosmetics, drugs, and some foods. Parabens can be ingested or absorbed through the skin. Some evidence suggests that par... obesity epigenetics satiety neurons
Read moreCardiorespiratory fitness is a measure of the body's ability to deliver oxygen to skeletal muscles during sustained physical activity. Findings from a new study suggest that higher cardiorespiratory fitness may increase the brain's gray matter. Gray matter contains the cell bodies, dendrites, and axon terminals of neurons in the brain. Loss of gray matter is associated with cognitive decline and memory loss – hallmarks of dementia. Physical inactivity promotes gray matter losses and is a major risk factor for dementia (https://www.ncbi.nlm.nih.gov/pubmed/21775213). The new study involved more... exercise brain aging neurons
Read moreDr. Rhonda Patrick makes her fifth appearance on the Joe Rogan Experience. ... nutrition vitamin d metabolism diabetes telomeres omega-3 inflammation depression dna damage stem cells micronutrients mitochondria autophagy autism schizophrenia resveratrol sulforaphane insulin blue light
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