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        [Story] Fish oil supplement use is linked to a lower risk of severe fatty liver disease. 
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      Non-alcoholic fatty liver disease (NAFLD), now usually termed metabolic dysfunction-associated steatotic liver disease (MASLD), affects about one in four people worldwide and can progress to serious liver injury and even liver cancer. Because there are only limited pharmacologic options to prevent its progression, researchers are also looking closely at diet and supplements as possible tools. A new large study examined whether people who regularly take fish oil supplements face a lower risk of developing severe forms of this disease. 
Using data from the UK Biobank, investigators followed 488,...
          <span class="search-tag">fatty liver</span>
          <span class="search-tag">omega-3</span>
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        [Podcast] Dr. Ben Bikman: How To Reverse Insulin Resistance Through Diet, Exercise, &amp; Sleep
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      Dr. Ben Bikman and Rhonda Patrick discuss the primary causes of insulin resistance and how to reverse it in as little as 90 days.
...
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">insulin</span>
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          <span class="search-tag">diabetes</span>
          <span class="search-tag">saturated fat</span>
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        [Story] Higher-dose omega-3 supplementation elevates blood levels, even in Alzheimer’s high-risk APOE4 carriers, but obesity may hinder its brain availability.
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      Omega-3 fatty acids play critical roles in maintaining brain health and function, potentially reducing the risk of developing Alzheimer&#39;s disease. People who carry the APOE4 gene variant and those with obesity have a higher risk of developing the disease, suggesting that differences in metabolism could be a factor. A 2022 study found that obesity influenced the amount of omega-3 in plasma phospholipid form that is important for brain transport.
Fifty people (half of whom carried the APOE4 gene) took 2.5 grams of combined docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) daily for six ...
          <span class="search-tag">brain</span>
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">obesity</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">genetics</span>
          <span class="search-tag">dementia</span>
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        [Topic] Omega-3 fatty acids
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      ...of potentially unreliable biomarkers, a factor that may produce hard-to-interpret results. 
Long-term measure of omega-3 intake
[tweetbox text=&#39;&quot;[The <span class="text-highlight">Omega-3 Index</span>] really is just a risk factor like cholesterol, except this is one that you can modify easily...you can just eat more fish or take supple...
          <span class="search-tag">cancer</span>
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          <span class="search-tag">mental health</span>
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        [Story] Omega-3 fatty acids protect against DNA damage.
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      Cellular DNA is subject to tens of thousands of injuries each day that arise from both endogenous sources, such as free radicals produced during normal metabolism, and exogenous sources, such as cytotoxic drugs, ionizing radiation, and cigarette smoke, among others. DNA damage induces genomic instability, a hallmark of aging (https://www.foundmyfitness.com/topics/hallmarks-of-aging). Evidence from a 2020 study suggests that omega-3 fatty acids protect against DNA damage. 
The study involved 140 healthy children and adolescents (aged 9 to 13 years). Researchers assessed the children&#39;s body meas...
          <span class="search-tag">omega-3</span>
          <span class="search-tag">dna damage</span>
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        [Topic] Blood-brain barrier
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      ...educe inflammation. Learn more about omega-3s and brain health in our comprehensive overview article. (https://www.foundmyfitness.com/topics/omega-3)
<span class="text-highlight">Omega-3 Index</span> validation: The <span class="text-highlight">Omega-3 Index</span> is a biomarker of omega-3 fatty acids in red blood cells, providing a more accurate assessment of omega-3 s...
          <span class="search-tag">omega-3</span>
          <span class="search-tag">immune system</span>
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          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">gut</span>
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        [Story] EPA and DHA supplementation increases serum testosterone levels in males with overweight and obesity.
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      Long-chain omega-3 fatty acids, such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), increase serum testosterone levels in mice, although the mechanisms that drive these benefits are unclear. While omega-3 fatty acids improve cellular function, omega-6 fatty acids serve as precursors to pro-inflammatory cytokines, such as arachidonic acid, which damage cells. Findings from a recent report detail the effects of long-chain omega-3 fatty acids and omega-6 fatty acids on serum testosterone levels in adults with overweight and obesity.
Omega-3 fatty acids are essential nutrients foun...
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          <span class="search-tag">testosterone</span>
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        [Topic] Brain-derived neurotrophic factor (BDNF)
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      [toc position=&#39;left&#39;]
Brain-derived neurotrophic factor, or BDNF, is a growth factor relevant to aging, brain function, behavior, metabolism, energy expenditure, and satiety. BDNF serves as a cell signaling protein, plays vital roles in numerous signaling pathways associated with a variety of disorders ranging from depression, (https://www.foundmyfitness.com/topics/depression) schizophrenia, and addiction to obesity and diabetes, and may serve as a hormone. It is perhaps best known for its influence on the formation, growth, survival, and development of neurons and for its role in mediating th...
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        [Podcast] Dr. Dale Bredesen on Preventing and Reversing Alzheimer&#39;s Disease
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      Dr. Dale Bredesen discusses treatments that may reverse symptoms of mild cognitive decline and Alzheimer’s disease.
...
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">diet</span>
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          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">dementia</span>
          <span class="search-tag">insulin</span>
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