Exposure to a high-fat, obesogenic diet during pregnancy and breastfeeding may contribute to poor eating habits and obesity later in life, a new study in mice shows. Mice whose mothers ate an unhealthy diet tended to overeat and gain more weight than mice whose mothers ate a healthy diet. Researchers fed female mice one of two diets – a high-fat, obesogenic chow, or a balanced, healthy chow – before, during, and after their pregnancies and lactation. After weaning, the animals' pups were given unlimited access to healthy chow initially and then allowed unlimited access to the high-fat obesoge... obesity pregnancy
Read moreOmega-3 supplementation during pregnancy promotes brown fat formation in offspring. A new study in mice showed that omega-3 fatty acid consumption during pregnancy and lactation promoted the formation of brown fat in offspring. Omega-3s also increased energy expenditure and cold resistance. Researchers fed female mice either a diet rich in omega-3 fatty acids or a diet devoid of omega-3s throughout their pregnancies and lactation. They measured their offspring's brown fat and energy expenditure and assessed their capacity to maintain their core body temperature in cold temperatures. They fou... metabolism omega-3 development metabolic syndrome brown fat
Read moreChildren performed better on tests after they exercised, a new study has found. The children also exhibited better cognitive control – the ability to focus on a task and act based on choice rather than impulse (https://pubmed.ncbi.nlm.nih.gov/16580701/). Researchers asked 20 preadolescent boys and girls to walk on a treadmill for 20 minutes at a brisk pace sufficient to raise their heart rate to 60 percent of their estimated maximum. After their heart rate returned to nearly pre-exercise levels, the children completed cognitive control assessments and standardized tests in reading, spelling, a... lactate exercise memory cognition
Read moreAerobic exercise – especially high-intensity exercise – reduces symptoms of anxiety, an analysis of 15 studies shows. These anti-anxiety effects endured for several months after cessation of the exercise. Reviewers analyzed data from 15 studies that investigated the effects of low- or high-intensity exercise on anxiety symptoms. All the participants in the studies had some degree of anxiety, with their conditions falling on a spectrum that included anxiety disorders, raised anxiety levels, and raised anxiety sensitivity (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881589/) – a condition in ... exercise depression anxiety blood-brain barrier lactate
Read moreBreastfeeding may reduce fatty deposits around the heart and other organs. The benefits of breastfeeding on infant health are widely known, but breastfeeding benefits maternal health, too. For example, evidence suggests that women who breastfeed experience a faster return to pre-pregnancy weight and have a lower risk of developing cardiovascular disease (https://pubmed.ncbi.nlm.nih.gov/30871389/) and certain types of cancer (https://pubmed.ncbi.nlm.nih.gov/34304962/) Findings from a 2021 study suggest that breastfeeding is associated with having less pericardial and visceral adipose tissue. ... cancer pregnancy development breast milk visceral fat
Read moreThis is an interesting rodent study. The problem is, however, broccoli sprouts are not usually advisable for women that are pregnant because they can be a source of foodborne illness. If proven safe, however, it seems (at the surface) plausible that there could be ways to reduce the risk of in the future. Perhaps through supplementation? FTA: > Methods: Pregnant Long-Evans rats were administered i.p. Injections of saline (100 μl) or lipopolysaccharide (LPS, 200 μg/kg), every 12 h on embryonic day (E) 19 and 20. In the treatment groups, dams were supplemented with 200 mg/day of dried BrSp fr... nutrition brain diet development sulforaphane protein lipopolysaccharide
Read moreLow-dose penicillin taken late in pregnancy and in early life increased aggression, impaired social behavior and anxiety-like behavior, increased inflammation in the brain, and led to permanent changes in the gut microbiome in mice. Concurrent supplementation with the probiotic, Lactobacillus rhamnosus JB-1, prevented some of these alterations. βeta-lactam antibiotics are the most frequently prescribed drugs given to infants and children. Several clinical studies have shown an association between early life antibiotic use and an increased risk of developing allergies, inflammatory bowel diseas... brain microbiome inflammation behavior antibiotics
Read moreDr. Rhonda Patrick makes her third appearance on the Joe Rogan Experience. ... brain nutrition exercise alzheimer's cholesterol omega-3 inflammation depression probiotics dna damage stem cells serotonin mental health cannabinoid curcumin
Watch nowFTA: > Parkinson's disease affects neurons in the Substantia nigra brain region -- their mitochondrial activity ceases and the cells die. Researchers now show that supplying D-lactate or glycolate, two products of the gene DJ-1, can stop and even counteract this process. They also showed that the two substances rescued the toxic effects of the weed killer Paraquat. Cells that had been treated with this herbicide, which is known to cause a Parkinson's like harm of mitochondria, recovered after the addition of the two substances. ... brain parkinson's tissue repair mitochondria neurons lactate
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