From the article:
The research team studied female rats without ovaries to mimic human menopause. They administered standardized tests that measured anxiety and assessed short-term recognition of objects and spatial memory (memory of temporary locations and the relationships between objects in space). The menopausal rats showed higher levels of anxiety and a decrease in recognition memory compared to an age-matched control group. There was no difference in spatial memory between the two groups. These results suggest that normal hormone imbalances contribute to some of the emotional symptoms associated with menopause, such as anxiety, as well as minor memory problems.