Exercise causes acute elevation of IL-6 which reduces postprandial blood glucose levels and insulin secretion by delaying gastric emptying.

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Exercise causes acute elevation of IL-6 which reduces postprandial blood glucose levels and insulin secretion by delaying gastric emptying in men with type 2 diabetes.

IL-6 is a cytokine with both negative and positive effects. Chronic elevation of IL-6 reflects ongoing inflammation and is linked to type 2 diabetes and atherosclerosis. In contrast, acute elevation of IL-6 from exercise inhibits inflammatory cytokines and stimulates the production of anti-inflammatory cytokines in humans.

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