Dr. Rhonda Patrick and Dr. Arthur Brooks explore the science of happiness and how to live a more meaningful life. ... mental health anxiety social media stress behavior meditation dopamine brain depression
Watch nowColds undermine the health and well-being of millions each year, yet few effective strategies exist to prevent infection or cut recovery time. Researchers in Japan tested whether a broccoli seed extract that supplies sulforaphane glucosinolate, a precursor of the phytochemical sulforaphane, could lessen cold symptoms in people who say they catch colds easily. The trial enrolled 66 healthy Japanese adults and randomly assigned them to take either the extract (100 mg sulforaphane glucosinolate per day) or a placebo powder for eight weeks. Broccoli seed extract improved several outcomes: On av... immune system sulforaphane virus
Read more[toc position='right'] When we engage in high-intensity exercise, our muscles become mini biochemical laboratories (https://www.youtube.com/watch?v=YXl1evV_spo), synthesizing compounds like lactate and myokines that circulate throughout the body and travel to our organs, where they exert a variety of signaling effects, including the synthesis of brain-derived neurotrophic factor (BDNF) (https://bdnfprotocols.com/)in the brain. Some of these molecules have anti-cancer properties. Vigorous exercise is also the most potent way to increase your VO2 max, also known as cardiorespiratory fitness, wh... exercise brain bdnf aerobic cardiovascular mortality aging exercise snacks
Read more[toc position='left'] Thymic involution is the process by which the thymus shrinks with age and produces fewer T cells, impairing immunity and increasing the risk of infection in older adults. In addition, thymic involution increases the risk of cancer and autoimmunity with age. However, research has identified some of the mechanisms of thymic involution and highlighted possible strategies to improve immunity: By activating PPAR-gamma, a protein that regulates fat metabolism, caloric restriction reduced the rate of thymic involution in mice and increased the number and diversity of circulatin... thymic involution immune system thymus autoimmunity
Read moreEffect of aerobic exercise on cancer in mice: > Training mice regularly on a wheel (the mouse version of a treadmill) decreased the growth of multiple types of tumors, including skin, liver, and lung cancers. Furthermore, mice that exercised regularly had a smaller chance of developing cancer in the first place. The beneficial effects of running went beyond tumor formation and growth, extending to cancer-associated weight loss, a process termed cachexia that is seen in cancer patients. Mice that exercised regularly showed no signs of cancer-associated weight loss in the researchers' lung ca... exercise cancer immune system aerobic il-6
Read moreAutism – often referred to as autism spectrum disorder, or ASD – is a neurodevelopmental disorder characterized by impaired social interaction and communication, as well as restrictive, repetitive patterns of behavior. The disorder typically manifests in early childhood and is slightly more common among boys than girls. Roughly one in 54 people living in the United States has ASD (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919599/). Findings from a recent clinical trial suggest that sulforaphane improves behavioral symptoms associated with autism. Sulforaphane is a bioactive compound derive... autism sulforaphane nrf2 myrosinase glucoraphanin
Read moreThis is an interesting rodent study. The problem is, however, broccoli sprouts are not usually advisable for women that are pregnant because they can be a source of foodborne illness. If proven safe, however, it seems (at the surface) plausible that there could be ways to reduce the risk of in the future. Perhaps through supplementation? FTA: > Methods: Pregnant Long-Evans rats were administered i.p. Injections of saline (100 μl) or lipopolysaccharide (LPS, 200 μg/kg), every 12 h on embryonic day (E) 19 and 20. In the treatment groups, dams were supplemented with 200 mg/day of dried BrSp fr... nutrition brain diet development sulforaphane protein lipopolysaccharide
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