Orthopedic implants need to bond firmly with surrounding bone while resisting microbes that can grow on their surfaces. Implants used after bone-cancer surgery face another challenge: limiting how many bone cancer cells remain alive on the implant surface. Researchers tested whether an implant coating could address these problems by locally delivering curcumin, a compound from turmeric, and ginger extract. This preclinical study used a titanium alloy commonly studied for load-bearing implants, coated with hydroxyapatite, a bone-like calcium phosphate. Some coatings also contained zinc oxide an... bone cancer curcumin
Read moreAlthough iron is essential for many physiological processes in the body, it can also be harmful, inducing oxidative stress and hindering neurogenesis. The body typically stores iron in protein complexes until needed, but these storage processes decline with age, leading to iron accumulation in body tissues. A recent study revealed that iron can build up in the brain, impairing cognitive function. Nevertheless, dietary components can help reduce iron accumulation in the brain and maintain cognitive health. Researchers examined the brain health of 72 cognitively healthy older adults by conductin... brain diet iron polyphenol
Read moreDr. Rhonda Patrick discusses fish oil and Afib risk, hyperbaric oxygen therapy, supplements for kids, and curcumin's impact on testosterone. ... rhonda sleep heart disease cholesterol omega-3 testosterone dementia curcumin supplements
Watch nowDr. Rhonda Patrick, Dr. Darya Rose, and Kevin Rose discuss turmeric's ability to increase detoxification enzymes through hormesis. ... diet exercise fasting
Watch nowCurcumin is the principal bioactive compound present in the yellow spice turmeric. An abundance of scientific evidence indicates that curcumin has antioxidant, anti-inflammatory, anticancer, and neuroprotective properties (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/) in humans. Findings from a 2019 study suggest that curcumin improves exercise tolerance in mice with heart failure via its activation of Nrf2. Heart failure, commonly referred to as the end stage of heart disease, affects more than 26 million people worldwide (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494150/). Exer... exercise heart disease curcumin antioxidant nrf2
Read moreBreast milk is a complex and highly dynamic fluid that contains both nutritional and non-nutritional components. Some of these components provide breast milk aroma and taste aspects, such as those associated with garlic or coffee, potentially influencing the breastfed infant's dietary preferences later in life (https://pubmed.ncbi.nlm.nih.gov/30982867/). Findings from a new study suggest that the non-nutritional compound piperine transfers into breast milk, providing pungent flavor aspects. Piperine is a bioactive compound found in black pepper that exerts anti-inflammatory, anti-pain, and an... nutrition breast milk
Read moreTim Ferriss and Dr. Rhonda Patrick discuss acute versus chronic inflammation and how supplemental antioxidants can reduce exercise benefits. ... inflammation exercise fasting stress mitochondria antioxidant
Watch nowDr. Darya Rose & husband Kevin Rose discuss the benefits of meditation, seasonal eating, and more. ... meditation podcast fasting
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