[toc position='left'] This post originally went out to subscribers to the FoundMyFitness newsletter. Sign up here to start receiving it! (https://www.foundmyfitness.com/newsletter) Protein is still (somehow) controversial. Should we restrict protein in favor of longevity and reducing cancer risk, or should we maximize our intake in favor of building muscle mass and enhancing performance? The answer lies somewhere in the middle. But one thing is for certain—the current recommendations don't accurately reflect the scientific evidence. That's why I sat down with Dr. Peter Attia as a guest on his ... aging cancer muscle strength protein exercise
Read moreDepression (https://www.foundmyfitness.com/topics/depression) is one of the most common mental health disorders worldwide—and one of the most debilitating. While conventional treatments like medication and cognitive behavioral therapy (CBT) can be effective, a growing body of research shows that physical activity deserves a seat at the table as a first-line treatment. A new meta-analysis examining 26 randomized controlled trials found that both aerobic and resistance training significantly reduced depressive symptoms—often to a degree comparable with more traditional interventions. Importantl... mental health anxiety exercise depression serotonin
Read more[toc position='left'] The blood-brain barrier comprises various membranes that separate the central nervous system (CNS) and the peripheral circulatory system. The purpose of this barrier is to allow the passage of nutrients and cell signals from the bloodstream to nerves and supporting cells in the CNS while excluding harmful substances. Genetic predispositions, environmental exposures, and aging may weaken the integrity of this barrier, allowing endotoxins and inflammatory immune cells to infiltrate the brain, contributing to accelerated brain aging and the risk of neurodegenerative diseases... omega-3 immune system blood-brain barrier brain alzheimer's gut obesity
Read more[toc position='left'] Nutrition in the first year of life is crucial to an infant's development and lifelong health. Early nutritional deficits are intrinsically linked to impaired mental and physical growth. Consequently, the risk of developing metabolic and cardiovascular diseases such as obesity, diabetes, and hypertension in childhood and later life is likely determined by early feeding and nutritional status. Breastfeeding is the biologically superior way to feed an infant. The American Academy of Pediatrics recommends exclusive breastfeeding for the first six months of an infant's life ... cancer breast cancer circadian rhythm nutrition brain microbiome heart disease diabetes inflammation alcohol stem cells immune system development intelligence
Read more[toc position='left'] Hyperthermia, a state of elevated core body temperature, stresses the body, activating molecular mechanisms that mitigate protein damage and aggregation and promote endogenous antioxidant, repair, and degradation processes. Whole-body hyperthermia is a therapeutic strategy used to treat various medical conditions, including cancer, fibromyalgia, and others.[ref doi='10.1093/annonc/mdf280'][ref doi='10.2147/CIA.S74949'][ref doi='10.3205/000235'] Emerging evidence suggests that whole-body hyperthermia might be useful in treating depression.[ref doi='10.1001/jamapsychiatry.2... sauna cancer depression
Read more[toc position='left'] Introduction [tweetbox text='"Modulation of autophagy may represent a promising therapeutic approach for extending human lifespan and healthspan."' tweet='"Modulation of autophagy may represent a promising therapeutic approach for extending human lifespan and healthspan." https://www.foundmyfitness.com/topics/autophagy'] Homeostasis, a cell's ability to maintain a constant internal environment, is essential to cell survival. It is predicated on achieving an equilibrium between the production and degradation of cellular components. One major pathway for degradation is auto... aging mitochondria autophagy nutrition exercise parkinson's cancer autoimmunity
Read moreAdults that were subjected to sleep deprivation for 36 hours experienced a 50% increase in a protein called tau that is linked to neuronal cell death and Alzheimer's disease. It has previously been shown that a single night of poor-quality sleep raised levels of A-beta, another protein linked to Alzheimer's disease, by 30%. Sleep is one of the most important determinants of brain health. Sleep is when the brain repairs itself and clears away buildup of aggregated proteins, cellular debris, and other harmful agents. One way this occurs is through the activation of the glymphatic system which is... alzheimer's sleep neurons protein
Read morePhthalates were 35% higher in participants who had eaten out the previous day compared with those who ate at home. Phthalates are ubiquitous in plastic products yet I have not phthalates listed on consumer product labels. Unfortunately, I'm not sure if it is required to be listed. In 2013, a randomized trial with five families that involved dietary replacement with organic foods that lacked plastic packaging found that phthalates increased 2000% during the trial because the chemical was found in organic imported spices and dairy products. Other studies have found that phthalates are excreted t... exercise hormones drug heat stress dairy
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