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      <h3 class="bold">
        [Podcast] Q&amp;A #65: Are Food Emulsifiers Harmful to Gut and Metabolic Health?
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      Dr. Rhonda Patrick discusses Akkermansia muciniphila, vitamin B1&#39;s effect on blood sugar, emulsifiers in food, and electrolyte supplements.
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        [Topic] Magnesium
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Introduction
Magnesium is an essential dietary mineral. It plays critical roles in myriad physiological processes, serving as a cofactor to more than 300 enzymes in the human body and maintaining the integrity of cellular structures and DNA. Magnesium deficiency is widespread, affecting more than half of people in the U.S. and increasing the risk of many chronic conditions, including cancer, metabolic disorders, and neurodegenerative diseases.  
At a glance, magnesium participates in: 
Enzymatic reactions, serving as a cofactor for more than 300 enzymes involved in variou...
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        [Topic] Toll-like receptors
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Toll-like receptors are a family of pattern recognition receptors expressed on the surface of immune and other cells. Toll-like receptors are the principal inducers of innate immunity[ref doi=&#39;10.1186/cc1471&#39;], activating transcription factors such as NF-kB that increase the expression of inflammatory cytokines. Among toll-like receptors, TLR4 is notable for recognizing lipopolysaccharide (LPS), a structure found on the outer membranes of Gram-negative bacteria. This overview will predominantly focus on TLR4 and its involvement in human health, disease, and behavior.
Toll...
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        [Podcast] Q&amp;A #27: Rhonda’s Ketogenic Diet—CGMs, Ketone Levels, &amp; Exercise
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</a>    <p>
      Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&amp;amp;A session.
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        [Topic] Quercetin
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Background
Quercetin is a bioactive compound that exerts antioxidant and anti-inflammatory properties.[ref pmid=&#39;26393898&#39;] Research indicates that quercetin may alleviate chronic health conditions such as hypertension, neurodegenerative disease, arthritis, and lung and kidney diseases and may be beneficial in combating aging-related diseases. Although much of the quercetin research has been performed in animals, some clinical trials have been conducted, and others are ongoing. 
A naturally occurring member of the flavonoid class of plant polyphenol (https://www.foundmyfi...
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        [Podcast] Joe Rogan Experience #1474 - Dr. Rhonda Patrick
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      Dr. Rhonda Patrick makes her ninth appearance on the Joe Rogan Experience.
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        [Topic] Metformin
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Metformin is a drug commonly used to treat type 2 diabetes. It is the fourth most widely prescribed medication in the United States, with more than 80 million prescriptions for the drug written yearly. Metformin is in a class of drugs called biguanides, which impede liver gluconeogenesis (glucose production in the liver), thereby decreasing glucose uptake in the gut and increasing overall glucose utilization by improving insulin sensitivity in skeletal muscle and fat tissue. Multiple studies demonstrate that metformin reduces fasting blood glucose levels by as much as 3.9...
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        [Topic] Depression
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Depression is a neuropsychiatric disorder characterized by negative mood, loss of interest in doing things, and metabolic, hormonal, and immune disturbances that can degrade a person&#39;s quality of life and increase their risk of disease and death. The World Health Organization estimates that approximately 322 million people – more than 4 percent of the global population – currently live with depression,[ref doi=&#39;10.1001/jama.2017.3826&#39;] the most common mental health disorder worldwide. Between 2005 and 2015 (the most recent years for which robust meta-analyses are availabl...
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        [Podcast] Dr. Charles Raison on Depression, the Immune-Brain Interface &amp; Whole-Body Hyperthermia
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      Dr. Charles Raison discusses the role inflammation plays in the development of depression in response to illness and stress. 
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        [Podcast] Dr. Pierre Capel on the Power of the Mind &amp; the Science of Wim Hof
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      Dr. Pierre Capel discusses cold stress, Wim Hof, genetic modification, and cancer immunotherapy.
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