Even a minor fall can cause a life-altering fracture for women with osteoporosis. Stronger bones can mean the difference between maintaining independence and facing long-term disability. A recent study found that combining high-intensity interval training (HIIT) with daily vitamin D supplements more than doubled the gains in bone mineral density compared to each intervention alone. Researchers enrolled 120 sedentary women aged 30 to 50, all diagnosed with osteoporosis. They randomly assigned participants to one of four groups: a control group, a vitamin D group (800 IU per day), an exercise-on... bone exercise
Read moreFrom the article: > "When we treated brain tissue from mice suffering from Alzheimer's disease with vitamin C, we could see that the toxic protein aggregates were dissolved. Our results show a previously unknown model for how vitamin C affects the amyloid plaques," says Katrin Mani, reader in Molecular Medicine at Lund University. Publication (http://dx.doi.org/10.1074/jbc.M111.243345) ... brain alzheimer's aging vitamin c dementia
Read moreSepsis is a potentially life-threatening condition caused by the body's innate immune response to acute infection. Under some circumstances, aspects of this response that are typically associated with defense against infection can induce extensive cell and tissue damage, leading to multiple organ failure, the hallmark of sepsis. Acute respiratory distress syndrome (ARDS) is a common sepsis-associated injury that can lead to respiratory failure and death. A 2019 phase 2 trial found that intravenous vitamin C reduced death rates among patients with sepsis and ARDS. The randomized, double-blind, ... vitamin c vitamin a
Read moreParticipants that were low in vitamin D at the start of the clinical trial were able to successfully raise the levels of the major form of circulating vitamin D (25-hydroxyvitamin D3) if they took a magnesium supplement along with their vitamin D supplement. Surprisingly, participants that had high 25-hydroxyvitamin D3 levels at the start of the trial actually lowered their levels to a more normal range after supplementing with magnesium and vitamin D. Both in vitro and animal studies have indicated that magnesium deficiency affects enzymes which synthesize and metabolize vitamin D metabolites... vitamin d magnesium vitamin a dairy
Read moreAround 93% of the people receiving the intravenous vitamin C are responding to chemotherapy and radiation, compared to 40% who usually do. The intravenous vitamin C may also show encouraging results in a small sample of people with glioblastoma. Remember that oral doses of vitamin C (even liposomal) can not achieve the same plasma concentrations that IVC can, which are between 800 to 1,000-fold higher. Other studies have revealed mechanisms by which the IVC works including the production of hydrogen peroxide which selectively kills cancer cells. Normal cells can detoxify the hydrogen peroxide ... cancer vitamin c vitamin a
Read moreOverall, the reduction in risk of respiratory infection induced by vitamin D was similar to the protective effect of the flu vaccine. The study analyzed data from 25 randomized clinical trials conducted in 14 countries including the UK, USA, Japan, India, Afghanistan, Belgium, Italy, Australia and Canada. ... vitamin d virus vitamin a
Read moreVitamin D extended lifespan by reducing the age-dependent formation of insoluble proteins.Proteins misfold and aggregate with age as a consequence of irreversible oxidation, nitration, and carbonylation of proteins, which impairs degradation of damaged proteins, and enhances aggregation. Aggregated proteins play a role in cardiovascular disease and neurodegenerative diseases like Alzheimer's disease. I talk more about the relationship between vitamin D and human aging in this video: https://www.youtube.com/watch?v=uc815fQn8iY I also elaborate on vitamin D supplementation, dose, bioavailabili... vitamin d aging vitamin a protein
Read moreI've talked previously about what I've referred to as the sweet spot: 40-60 ng/ml. Some studies have shown that the lowest all-cause mortality happens in that range. The upper range may be important because vitamin D can be toxic at very ranges. ... vitamin d cancer aging vitamin a
Read moreCatechins are bioactive compounds present in green tea. One well-known catechin, epigallocatechin gallate (EGCG), is a potent scavenger of reactive oxygen species and has demonstrated antioxidant, anti-inflammatory, and anticarcinogenic properties in both clinical and in vitro studies. Some evidence suggests that adding vitamin C to green tea might increase the bioavailability of the catechins present in green tea. Consumers of green tea commonly add milk, lemon, or other substances to their tea. To assess the impact that these additives have on catechin bioavailability, the authors of the st... vitamin c green tea vitamin a antioxidant
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