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        [Story] Ketone supplements marginally hinder high-intensity cycling performance, echoing earlier research.
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      Ketones are molecules produced by the liver during the breakdown of fatty acids. Supplemental ketones – referred to as endogenous ketones – are popular among many athletes due to their purported beneficial effects on performance. A new study shows that endogenous ketone supplementation impairs athletic performance in endurance athletes. 
Researchers asked 23 well-trained adult cyclists to consume a ketone supplement (providing 0.35 grams of ketones per kilogram body weight) or a placebo 30 minutes before completing a 20-minute cycling trial on an exercise bike. The participants repeated the cy...
          <span class="search-tag">exercise</span>
          <span class="search-tag">performance</span>
          <span class="search-tag">ketosis</span>
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        [Story] One in eight deaths in Americans ages 20 to 64 resulted from drinking too much alcohol, according to a U.S. population-based study.
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      More than 20 percent of deaths in the United States are attributable to alcohol. 
Nearly 13 percent of all deaths among young and middle-aged adults in the United States were caused by drinking too much alcohol, a new study finds. Among adults between the ages of 20 and 49 years, excessive alcohol consumption caused more than 20 percent of all deaths. 
Researchers reviewed alcohol consumption data from more than 2 million people living in the United States between 2015 and 2019. Then they looked at the rates and causes of death during the same period. 
They found that 12.9 percent of all death...
          <span class="search-tag">alcohol</span>
          <span class="search-tag">mortality</span>
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        [Podcast] Q&amp;A #32: Protein, mTOR &amp; IGF-1—Plus Rhonda’s Skincare Routine
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      Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&amp;amp;A session.
...
          <span class="search-tag">rhonda</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">breast cancer</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">probiotics</span>
          <span class="search-tag">coffee</span>
          <span class="search-tag">vitamin b12</span>
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          <span class="search-tag">nad+</span>
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        [Story] Long-lived adults have highly efficient DNA repair mechanisms.
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      Semi-supercentenarians and supercentenarians – people who live to the age of 105 years and beyond – personify healthy aging, having avoided the diseases and concomitant disabilities that many adults experience, such as cardiovascular disease, diabetes, cancer, and cognitive decline. Genetics play key roles in longevity and healthy aging. Findings from a recent study indicate that semi-supercentenarians and supercentenarians have unique genetic profiles characterized by highly efficient DNA repair mechanisms. 
DNA repair is a cellular defense mechanism that helps maintain genomic integrity. Res...
          <span class="search-tag">aging</span>
          <span class="search-tag">dna damage</span>
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        [Story] Chronic diseases linked to &quot;mismatched&quot; ancestral past and modern lifestyle patterns.
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      The global incidence of metabolic and cardiovascular diseases has increased markedly in recent decades, largely attributable to widespread adoption of Western dietary and lifestyle patterns that are in stark contrast to ancestral patterns – a phenomenon referred to as the mismatch hypothesis. Findings from a recent study demonstrate that a mismatch between the ancestral and modern lifestyle patterns contribute to increased risk for chronic diseases among the Turkana people. 
The Turkana in the arid regions of northwestern Kenya. The traditional Turkana diet, consisting primarily of meat, milk,...
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        [Story] Alterations in brain blood use contribute to motor deficits in type 2 diabetes in women.
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      People with type 2 diabetes often experience sensory and motor deficits. These deficits have been attributed to peripheral nerve damage that commonly occurs with the condition. Findings from a new study suggest that changes in brain blood use contribute to sensory and motor deficits associated with type 2 diabetes. 
Poor blood glucose control and insulin resistance – the hallmarks of type 2 diabetes – contribute to micro- and macrovascular changes in blood vessels. These changes promote a wide range of complications that affect multiple organ systems, including cardiovascular, neurological, an...
          <span class="search-tag">diabetes</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">blood sugar</span>
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