Multivitamins are among the most widely used dietary supplements, yet evidence that they influence biological aging remains limited. To see whether a simple daily multivitamin could affect that process, researchers tracked changes in epigenetic clocks, which are blood-based tools that estimate biological aging using chemical marks on DNA that influence how genes are used. This randomized, double-blind, placebo-controlled trial included 958 generally healthy participants from the COSMOS study, with an average age of 70. Blood samples were collected at the start of the study, after one year, an... cocoa epigenetics multivitamin
Read moreSarcopenia, the age-related decline in muscle mass and strength, exposes many older people to frailty, falls, and loss of independence. Exercise helps, yet the added value of antioxidant supplements in this setting is uncertain. Researchers in China asked whether vitamins C and E could boost the effects of a structured resistance training program in women already diagnosed with sarcopenia. The team enrolled 60 women aged 60 to 75 years who met Asian Working Group criteria for sarcopenia and randomly assigned them to two groups. One group received daily vitamin C (1000 milligrams) plus vitamin ... antioxidant exercise supplements
Read moreResearchers in the field of aging science have identified nine hallmarks of aging – observable biological patterns of dysfunction that occur as an organism a... ... aliquot epigenetics aging stem cells senescence
Listen nowHigher omega-3 fatty acid consumption could play a unique role in mitigating chronic inflammation by altering the methylation pattern of the interleukin-6 (IL-6) promoter, reducing the activity of this inflammatory cytokine. This epigenetic mechanism highlights omega-3's capacity to govern gene expression and shape the genetic landscape, transcending its contributions to cell membrane dynamics or mediator production and positioning its effects at the molecular blueprint level rather than merely fine-tuning cellular responses. The relationship between IL-6 and human health is multifaceted: Inte... omega-3 inflammation genetics
Read moreParkinson's disease is a progressive neurodegenerative disorder that affects more than 10 million people worldwide. The neuropathological hallmarks of Parkinson's disease are the loss of dopamine-producing neurons in the substantia nigra region of the brain and the aggregation of alpha synuclein, a type of protein. People who have Parkinson's disease experience both motor symptoms (such as tremors and a shuffling gait) and non-motor symptoms (such as pain, fatigue, and difficulty concentrating or remembering). Findings from a new study suggest that people with Parkinson's disease have defects ... parkinson's
Read moreSince COVID-19's emergence in late 2019, the disease has claimed the lives of nearly 5 million people worldwide. Scientists predict that SARS-CoV-2, the virus that causes COVID-19, will likely achieve endemic status (https://www.science.org/doi/full/10.1126/science.abe6522) in the coming years, so identification of strategies that bolster viral immunity and reduce negative outcomes is essential. Findings from a recent study suggest that optimal blood levels of vitamin D could markedly reduce the risk of death from COVID-19. Vitamin D regulates the expression of thousands of genes in the human ... covid-19
Read morePsilocybin is a bioactive psychedelic compound present in certain varieties of mushrooms, commonly referred to as "magic" mushrooms. With clinical trials finding psilocybin treatment to be effective at reducing symptoms of treatment-resistant depression (https://pubmed.ncbi.nlm.nih.gov/27210031/) and obsessive compulsive disorder (https://pubmed.ncbi.nlm.nih.gov/17196053/), increasingly more attention is being drawn to the potential mental health benefits of the compound. Findings from a recent study indicate that a single dose of psilocybin triggers a tangible and lasting proliferation of new... brain mushroom psychedelic lsd
Read moreHeart disease, including atheroslcerotic cardiovascular disease, is a leading cause of death worldwide. Its associated inflammation and metabolic dysfunction can be prevented with a diet high in nutrient dense foods such as those commonly found in the Mediterranean diet (https://www.mdpi.com/1422-0067/20/19/4716). Findings of a new report indicate that a high intake of vitamin K - a micronutrient found at high levels in common Mediterranean meals - might reduce the incidence of atherosclerotic disease. Atherosclerosis refers to the hardening of arteries due to the formation of plaques composed... heart disease vitamin k
Read moreCancer is a leading cause of death in the United States, but new therapies targeting diet and lifestyle may aid in fighting the disease. Emerging research suggests that modulating the kind of nutrients available to cancer cells may encourage or inhibit their growth (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329766/). Findings of a recent study detail the effects of polyunsaturated fats on cancer growth in mice. Polyunsaturated fats are fatty acids that have more than one unsaturated carbon bond in the molecule, such as omega-3 and omega-6 fatty acids. They are present in fish, nuts, and se... cancer omega-3 ketogenic diet
Read moreDr. Valter Longo discusses fasting as a means to treat or prevent age-related diseases such as cancer, Alzheimer’s disease, and others. ... fasting cancer obesity aging heart disease diabetes insulin resistance inflammation stem cells immune system tissue repair autophagy apoptosis insulin autoimmunity
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