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        [Story] Xanthan gum–a common food thickener–increased intestinal inflammation and signs of a leakier gut in rats. 
      </h3>
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      ...roups.
Body weight and blood markers of metabolic health did not clearly differ. The groups had similar food intake, weight gain, and body fat. Blood <span class="text-highlight">sugar</span> and measured blood fats, including triglycerides and cholesterol, were also similar. 
Xanthan gum may activate immune cells in the wall of the co...
          <span class="search-tag">gut</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">intestinal permeability</span>
          <span class="search-tag">ultra-processed foods</span>
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        [Story] A 6-hour eating window led to weight loss and improved hormonal markers in overweight or obese women with polycystic ovary syndrome. 
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      ...es lowered fasting insulin and HOMA-IR, a commonly used estimate of insulin resistance. 
TRE also reduced HbA1c, a marker that reflects average blood <span class="text-highlight">sugar</span> over about three months, while CR more clearly lowered fasting glucose and improved QUICKI, an estimate of insulin sensitivity. 
Common PCOS-rela...
          <span class="search-tag">hormones</span>
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">metabolism</span>
          <span class="search-tag">time-restricted eating</span>
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        [Topic] Urolithin A
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      ... T cells—especially the naive subset—became less dependent on glucose and more capable of oxidizing fats and amino acids. Instead of relying on quick <span class="text-highlight">sugar</span>, urolithin A pushed cells toward steadier, mitochondria-driven fuel, a sign of better metabolic fitness and resilience. Natural killer cells show...
          <span class="search-tag">immune system</span>
          <span class="search-tag">gut</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">prebiotics</span>
          <span class="search-tag">urolithin a</span>
          <span class="search-tag">microbiome</span>
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        [Story] Combining vitamin D supplementation with regular exercise shows a significant reduction in insulin resistance and improved lipid regulation, potentially offering an innovative approach to managing type 2 diabetes and related metabolic disorders.  
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      ...ay offer new potential for disease management. Researchers tested whether combining vitamin D supplementation with structured exercise improves blood <span class="text-highlight">sugar</span> control, lipid levels, and vitamin D status more than either approach on its own.
This work pooled 18 randomized controlled trials in adults, tot...
          <span class="search-tag">cholesterol</span>
          <span class="search-tag">diabetes</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">metabolism</span>
          <span class="search-tag">vitamin d</span>
          <span class="search-tag">triglycerides</span>
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        [Podcast] The Science of Exercise for Cancer | Kerry Courneya, PhD
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      Dr. Kerry Courneya and Dr. Rhonda Patrick discuss the remarkable science behind exercise oncology.
...
          <span class="search-tag">cancer</span>
          <span class="search-tag">exercise</span>
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        [Topic] Beta-hydroxybutyrate
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      ...rugs used to treat type 2 diabetes that reduce the reuptake of glucose in the kidney, increasing the amount of glucose in the urine, decreasing blood <span class="text-highlight">sugar</span> levels, and increasing the production of ketones by the liver.[ref doi=&#39;10.1111/dom.13488&#39;] 
Effects on cellular senescence
Research in rodents a...
          <span class="search-tag">butyrate</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">fasting</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">ketosis</span>
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        [Topic] Quercetin
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      ...tinib/quercetin combination for IPF and diabetes-related kidney fibrosis. 
Pharmacokinetics
Quercetin found in food occurs as glycosides — bound to a <span class="text-highlight">sugar</span> molecule — while the supplemental form of quercetin usually occurs as an aglycone. After ingesting quercetin glycosides, beta-glucosidases, enzym...
          <span class="search-tag">aging</span>
          <span class="search-tag">antioxidant</span>
          <span class="search-tag">nutrition</span>
          <span class="search-tag">inflammation</span>
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        [Topic] Caloric restriction
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      ...s were similar in caloric content (30 percent restriction) but differed in overall nutrient and fiber content. The UW diet was considerably higher in <span class="text-highlight">sugar</span> (sucrose) than the NIA diet. In addition, the feeding schedules on which the monkeys ate differed, with the UW monkeys allowed to eat freely duri...
          <span class="search-tag">diet</span>
          <span class="search-tag">aging</span>
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        [Topic] Nicotinamide riboside
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      ...icial to health and may delay or prevent the onset of age-related disease. 
Obesity
In a study in which mice were fed a diet that was high in fat and <span class="text-highlight">sugar</span> and received a 400-milligram per kilogram of body weight (mg/kg/bw) nicotinamide riboside supplement every day for one week, the mice gained 60 p...
          <span class="search-tag">obesity</span>
          <span class="search-tag">nad+</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">breast milk</span>
          <span class="search-tag">cardiovascular</span>
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