Poor diet quality increases symptom severity in children with ADHD. Attention deficit hyperactivity disorder (ADHD) is a neuro-behavioral condition characterized by inattention, impulsive behavior, and emotional dysregulation. The condition affects as many as 10 percent of children (https://www.tandfonline.com/doi/abs/10.1080/15374416.2017.1417860) living in the United States and is more common among males than females (https://www.sciencedirect.com/science/article/pii/B9780702033971000148). Findings from a recent study suggest that poor diet quality increases symptom severity in children wit... nutrition adhd
Read more[toc position='left'] The blood-brain barrier comprises various membranes that separate the central nervous system (CNS) and the peripheral circulatory system. The purpose of this barrier is to allow the passage of nutrients and cell signals from the bloodstream to nerves and supporting cells in the CNS while excluding harmful substances. Genetic predispositions, environmental exposures, and aging may weaken the integrity of this barrier, allowing endotoxins and inflammatory immune cells to infiltrate the brain, contributing to accelerated brain aging and the risk of neurodegenerative diseases... omega-3 immune system blood-brain barrier brain alzheimer's gut obesity
Read more[toc position='left'] Toll-like receptors are a family of pattern recognition receptors expressed on the surface of immune and other cells. Toll-like receptors are the principal inducers of innate immunity[ref doi='10.1186/cc1471'], activating transcription factors such as NF-kB that increase the expression of inflammatory cytokines. Among toll-like receptors, TLR4 is notable for recognizing lipopolysaccharide (LPS), a structure found on the outer membranes of Gram-negative bacteria. This overview will predominantly focus on TLR4 and its involvement in human health, disease, and behavior. Toll... toll-like receptors gut aging microbiome inflammation immune system intestinal permeability omega-3 endotoxemia
Read more[toc position='left'] A single layer of epithelial cells lines the entire digestive tract, facilitating the exchange of nutrients between the intestine and the bloodstream. This layer, referred to as the intestinal epithelium, must be permeable to nutrients yet impermeable to pathogens. [tweetbox text='"Increased intestinal permeability (also known as "leaky gut") allows pathogens to leak through the intestinal barrier and pass directly into the bloodstream, promoting inflammation."' tweet='"Increased intestinal permeability (also known as "leaky gut") allows pathogens to leak through the int... intestinal permeability butyrate gut microbiome polyphenol autoimmunity
Read moreDepression is a complex neuropsychiatric disorder that affects millions of people worldwide. Although many factors contribute to a person's risk for developing depression, such as childhood trauma or stressful life events, genetic predisposition for the condition plays a prominent role (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065213/). Findings from a recent study suggest that air pollution exerts harmful neuropsychiatric effects, especially among people genetically predisposed to depression. Air pollution contains myriad toxic substances, including chemicals, gases, and particulate mat... depression pollution
Read moreCognitive function, including complex executive functions like working memory and basic functions like sensory processing, progressively declines with age. While executive function loss is highly variable and easily measurable in older adult populations, younger adults usually perform at a level consistent with their peers, which makes studying cognitive decline in younger adults difficult. In a 2014 report, researchers measured visual processing ability in young adults before and after supplementation with lutein and zeaxanthin. Visual processing refers to the brain’s ability to utilize and ... brain eyes carotenoids
Read more[toc position='left'] Nutrition in the first year of life is crucial to an infant's development and lifelong health. Early nutritional deficits are intrinsically linked to impaired mental and physical growth. Consequently, the risk of developing metabolic and cardiovascular diseases such as obesity, diabetes, and hypertension in childhood and later life is likely determined by early feeding and nutritional status. Breastfeeding is the biologically superior way to feed an infant. The American Academy of Pediatrics recommends exclusive breastfeeding for the first six months of an infant's life ... cancer breast cancer circadian rhythm nutrition brain microbiome heart disease diabetes inflammation alcohol stem cells immune system development intelligence
Read more[toc position='left'] Salmon roe – sometimes referred to as "salmon caviar" – is the internal egg mass found in female salmon. It is served in a variety of dishes, including sushi and pasta, or as a garnish or condiment to seafood or eggs. Salmon roe is rich in protein, vitamins, astaxanthin, and the omega-3 fatty acids eicosapentaenoic acid, or EPA, and docosahexaenoic acid, or DHA. Omega-3 fatty acids are long-chain polyunsaturated fatty acids. They are considered essential fatty acids because the human body cannot make them. Alpha-linolenic acid, or ALA, an omega-3 fatty acid that serves a... brain aging omega-3 diet mental health dementia alzheimer's
Read more[toc position='left'] Depression is a neuropsychiatric disorder characterized by negative mood, loss of interest in doing things, and metabolic, hormonal, and immune disturbances that can degrade a person's quality of life and increase their risk of disease and death. The World Health Organization estimates that approximately 322 million people – more than 4 percent of the global population – currently live with depression,[ref doi='10.1001/jama.2017.3826'] the most common mental health disorder worldwide. Between 2005 and 2015 (the most recent years for which robust meta-analyses are availabl... inflammation probiotics circadian rhythm meditation behavior heat stress depression metabolism neurotransmitter nutrition exercise brain microbiome interesting omega-3
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