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        [Topic] Exercise for Depression
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      Depression (https://www.foundmyfitness.com/topics/depression) is one of the most common mental health disorders worldwide—and one of the most debilitating. 
While conventional treatments like medication and cognitive behavioral therapy (CBT) can be effective, a growing body of research shows that physical activity deserves a seat at the table as a first-line treatment. A new meta-analysis examining 26 randomized controlled trials found that both aerobic and resistance training significantly reduced depressive symptoms—often to a degree comparable with more traditional interventions. Importantl...
          <span class="search-tag">mental health</span>
          <span class="search-tag">anxiety</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">depression</span>
          <span class="search-tag">serotonin</span>
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        [Topic] Melatonin
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Introduction
Melatonin isn’t just the “sleep hormone”—it regulates over 500 genes and plays a key role in the body’s antioxidant defenses.
As we age, melatonin production declines significantly. By the time a person reaches 50 years old, melatonin levels are 50% of what they were at age 20. By age 80, melatonin production can be ten times lower than in teenagers. (https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2022.888292/full) This reduction in melatonin is linked to changes in sleep patterns, circadian rhythm disruption, and overall healt...
          <span class="search-tag">melatonin</span>
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">parkinson&#39;s</span>
          <span class="search-tag">sleep</span>
          <span class="search-tag">circadian rhythm</span>
          <span class="search-tag">dementia</span>
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        [Story] Vitamin D and magnesium co-supplementation improves behavior and mental health in children with ADHD.
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      Attention-deficit/hyperactivity disorder (ADHD) is a common neurobehavioral condition. Characterized by inattention and/or hyperactive or impulsive behavior that interferes with functioning, learning, or development, ADHD affects as many as 7 percent of children (https://pubmed.ncbi.nlm.nih.gov/29033005/) and nearly 3 percent of adults (https://pubmed.ncbi.nlm.nih.gov/31675080/) worldwide. Findings from a study published earlier this year suggest that vitamin D and magnesium co-supplementation improves behavior and mental health in children with ADHD. 
A growing body of evidence suggests that ...
          <span class="search-tag">vitamin d</span>
          <span class="search-tag">adhd</span>
          <span class="search-tag">magnesium</span>
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        [Podcast] NAD+ in Aging: Role of Nicotinamide Riboside and Nicotinamide Mononucleotide
      </h3>
</a>    <p>
      Rhonda explains NAD+: importance for aging, decline with age, boosters (nicotinamide riboside, nicotinamide mononucleotide), and data in animals and humans.
...
          <span class="search-tag">aging</span>
          <span class="search-tag">dna damage</span>
          <span class="search-tag">genetics</span>
          <span class="search-tag">resveratrol</span>
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        [Topic] Nicotinamide mononucleotide
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Nicotinamide mononucleotide (NMN) is a precursor molecule for the biosynthesis of nicotinamide adenine dinucleotide, or NAD+, a coenzyme that participates in the production of cellular energy and DNA repair. NAD+ can also be synthesized from other precursors including nicotinamide (NAM, also called niacinamide), nicotinic acid (NA), and nicotinamide riboside (NR), which are often collectively referred to as niacin (vitamin B3) or niacin equivalents.[ref doi=&#39;10.12688/f1000research.12120.1&#39;] These precursors are not equally allocated throughout the body; rather, they exhib...
          <span class="search-tag">aging</span>
          <span class="search-tag">obesity</span>
          <span class="search-tag">neurodegeneration</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">cancer</span>
          <span class="search-tag">dna damage</span>
          <span class="search-tag">mitochondria</span>
          <span class="search-tag">nad+</span>
          <span class="search-tag">cardiovascular</span>
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        [Topic] NAD+
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Nicotinamide adenine dinucleotide (NAD+) is a cofactor (a molecule that assists enzymes in chemical reactions) that plays an essential role in multiple physiological processes, such as energy metabolism, DNA repair, and immune activation. It is necessary for the activity of sirtuins, a class of enzymes involved in longevity, and poly-ADP-ribose polymerases (PARPs), a family of DNA-repair enzymes. Cellular NAD+ production declines with age, however, and its depletion likely drives the onset and progression of multiple age-related conditions such as metabolic dysregulation ...
          <span class="search-tag">metabolism</span>
          <span class="search-tag">mitochondria</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">dna damage</span>
          <span class="search-tag">circadian rhythm</span>
          <span class="search-tag">nad+</span>
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        [Story] Exercise training increased the activity of genes involved in the mood-enhancing effects of tryptophan metabolism via the kynurenine pathway in health
      </h3>
</a>    <p>
      Exercise is more effective than medicine in reducing visceral fat according to a meta-analysis of 17 randomized controlled trials.
Visceral fat is also known as abdominal fat and is involved in systemic inflammation through the production of adipokines. Visceral fat is linked to type 2 diabetes, certain types of cancer, heart disease and more.
...
          <span class="search-tag">exercise</span>
          <span class="search-tag">depression</span>
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        [Podcast] Dr. Charles Raison on Depression, the Immune-Brain Interface &amp; Whole-Body Hyperthermia
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      Dr. Charles Raison discusses the role inflammation plays in the development of depression in response to illness and stress. 
...
          <span class="search-tag">depression</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">immune system</span>
          <span class="search-tag">behavior</span>
          <span class="search-tag">mental health</span>
          <span class="search-tag">psychedelic</span>
          <span class="search-tag">sauna</span>
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