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        [Story] Higher cardiorespiratory fitness may be linked to greater energy-use capacity in immune cells. 
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      Exercise has long been linked to better immune health, but much less is known about what happens inside individual immune cells as fitness increases. A new study examined how cardiorespiratory fitness is linked to energy use and signaling in cytotoxic T cells, immune cells that help destroy infected or abnormal cells.
The study included 43 healthy adults aged 20 to 40. Each participant completed a demanding cycling test to estimate their aerobic fitness, meaning how well the body delivers and uses oxygen during hard exercise. Using resting blood samples, researchers analyzed cytotoxic T cells ...
          <span class="search-tag">exercise</span>
          <span class="search-tag">immune system</span>
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        [Story] Movement-related abdominal pressure shapes the brain&#39;s cleanup system. 
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      The brain&#39;s cleanup system, often called the glymphatic system, uses the movement of cerebrospinal fluid to help carry waste away from brain tissue. That process is best known for its activity during sleep, but less is known about how brain fluid moves during wakefulness. A new study tested whether movement-related contractions of the abdominal muscles (the muscles in the belly wall) could create pressure changes that reach the brain and shift those fluids. 
The researchers studied mice while they moved on a spherical treadmill, using high-speed brain imaging to track tiny shifts in the top su...
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">dementia</span>
          <span class="search-tag">exercise</span>
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        [Story] Hot baths improved cardiorespiratory fitness in endurance runners by boosting red blood cell mass and heart function. 
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      Endurance athletes often look for ways to increase cardiorespiratory fitness beyond what exercise alone can provide, yet many proven methods are expensive and require major logistical demands. In a new study, researchers tested whether hot baths offer a simpler approach to stimulate cardiovascular adaptations. 
The study enrolled 10 well-trained endurance runners with an average maximal oxygen consumption (VO₂max, the highest rate of oxygen use during intense exercise) of about 64 milliliters per kilogram per minute. Each runner completed two five-week blocks: one with hot water immersion and ...
          <span class="search-tag">exercise</span>
          <span class="search-tag">heat stress</span>
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        [Podcast] Q&amp;A #72: What Causes Fragmented Sleep—and Which Lipid Markers Best Predict Heart Risk?
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      Dr. Rhonda Patrick discusses fragmented sleep, lipid biomarkers including ApoB and LP(a), coffee makers and bean quality, and choline supplementation.
...
          <span class="search-tag">biomarkers</span>
          <span class="search-tag">heart disease</span>
          <span class="search-tag">coffee</span>
          <span class="search-tag">sauna</span>
          <span class="search-tag">supplements</span>
          <span class="search-tag">sleep</span>
          <span class="search-tag">rhonda</span>
          <span class="search-tag">Microplastics</span>
          <span class="search-tag">Ubiquinol</span>
          <span class="search-tag">magnesium</span>
          <span class="search-tag">L-Theanine</span>
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        [Podcast] Q&amp;A #54: Can Glycine and Inositol Improve Sleep?—Plus Melatonin as an Antioxidant
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      Dr. Rhonda Patrick explores melatonin&#39;s antioxidant properties, curcumin supplementation, antinutrients, and SARMs in her latest Q&amp;amp;A.
...
          <span class="search-tag">rhonda</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">cancer</span>
          <span class="search-tag">sleep</span>
          <span class="search-tag">melatonin</span>
          <span class="search-tag">curcumin</span>
          <span class="search-tag">sulforaphane</span>
          <span class="search-tag">berberine</span>
          <span class="search-tag">moringa</span>
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        [Podcast] Dr. Martin Gibala: The Science of Vigorous Exercise — From VO2 Max to Time Efficiency of HIIT
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      Dr. Martin Gibala discusses HIIT&#39;s health benefits and describes common HIIT protocols.
...
          <span class="search-tag">exercise</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">heart disease</span>
          <span class="search-tag">diabetes</span>
          <span class="search-tag">mitochondria</span>
          <span class="search-tag">cortisol</span>
          <span class="search-tag">fat</span>
          <span class="search-tag">muscle</span>
          <span class="search-tag">bone</span>
          <span class="search-tag">lactate</span>
          <span class="search-tag">exercise snacks</span>
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        [Podcast] Q&amp;A #43: Rhonda’s Diet and Supplements—Plus Menopausal Hormone Therapy
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</a>    <p>
      Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&amp;amp;A session.
...
          <span class="search-tag">rhonda</span>
          <span class="search-tag">vitamin d</span>
          <span class="search-tag">microbiome</span>
          <span class="search-tag">hormones</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">melatonin</span>
          <span class="search-tag">bone</span>
          <span class="search-tag">time-restricted eating</span>
          <span class="search-tag">cardiovascular</span>
          <span class="search-tag">supplements</span>
          <span class="search-tag">menopause</span>
          <span class="search-tag">Hair</span>
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        [Podcast] Q&amp;A #37: Why ApoB Stays High—and How Omega-3s, Diet, &amp; Gut Health May Lower It
      </h3>
</a>    <p>
      Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&amp;amp;A session.
...
          <span class="search-tag">rhonda</span>
          <span class="search-tag">vitamin d</span>
          <span class="search-tag">gut</span>
          <span class="search-tag">ketosis</span>
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">fasting</span>
          <span class="search-tag">sulforaphane</span>
          <span class="search-tag">intestinal permeability</span>
          <span class="search-tag">nrf2</span>
          <span class="search-tag">urolithin a</span>
          <span class="search-tag">Hair</span>
          <span class="search-tag">menopause</span>
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        [Story] Previous infection with SARS-CoV-2 plus vaccination protects against variants.
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      The delta variant of SARS-CoV-2, the virus that causes COVID-19, is one of multiple variants to exhibit increased resistance to antibodies as well as higher transmissibility. It is unclear if vaccination or prior infection with the original Wuhan Hu-1 strain is effective against these emerging variants. But now, a new report suggests individuals who have recovered from infection with the original SARS-CoV-2 strain are protected from variants such as delta, especially following vaccination.
A virus strain is considered the &quot;parent&quot; form of a virus. For example, SARS-CoV-1 and SARS-CoV-2 are str...
          <span class="search-tag">vaccine</span>
          <span class="search-tag">covid-19</span>
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        [Story] Satchin Panda, Ph.D. on Time-Restricted Feeding and Its Effects on Obesity, Muscle Mass &amp; Heart Health
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</a>    <p>
      Dr. Panda&#39;s research and that of his colleagues has suggested a pretty straightforward solution that seems to show a lot of merit, and that is: time-restricted feeding. By restricting mice to a 12-hour window in which they can eat starting at the first bite of food but otherwise allowing them to eat the same amount of calories, they have shown that they can attain some pretty amazing benefits, including…
decreased fat mass
increased lean muscle mass
improved glucose tolerance
improved lipid profile
reduced inflammation
higher mitochondrial volume
protection from mild-age related fatty liver
in...
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