Q&A #37 with Dr. Rhonda Patrick (7/09/2022)
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In this Q&A, Dr. Rhonda Patrick answers audience questions on egg consumption, loading creatine, supplements for lowering ApoB, and much more. Timestamps include:
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Can alpha lipoic acid help control blood sugar levels?
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Does sauna have added benefits over simply using that time to exercise?
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Rhonda's current supplement routine
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The number of eggs you can safely eat in a day according to the American Heart Association
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Can creatine supplementation cause hair loss?
What is the role of the intestinal barrier in human health?
The intestinal barrier serves as a gatekeeper to the human body. The loss of the health and integrity of this barrier influences multiple aspects of human health – including cardiometabolic function, neurological health, behavior, and more – in surprising and unexpected ways. One of these ways involves lipopolysaccharide, or LPS, a bacterial product that arises in the intestine, and its interaction with far distal tissues and organs via the induction of immune mediators.[1]
"Increased intestinal permeability (also known as"leaky gut") allows pathogens to leak through the intestinal barrier and pass directly into the bloodstream, promoting inflammation."- Dr. Rhonda Patrick Click To Tweet
LPS exploits intestinal permeability.
Intrinsic to this interaction is the barrier's structure: a single-celled, semipermeable layer of epithelial cells held together by tight junctions and protected by a double layer of mucus – a haven for the commensal bacteria that reside in the gut. If the tight junctions between the cells degrade, gaps form, increasing the barrier's permeability. LPS exploits this permeability to gain access to the bloodstream. There, pattern-recognition molecules called toll-like receptors detect its presence and activate an immune response that drives the expression of an array of proinflammatory proteins and mediators.
This cascade of events, starting with the loss of barrier function and culminating with immune activation, likely plays roles in the pathogenesis of many chronic disorders, including cardiovascular disease, neurodegenerative disease, behavioral disorders, and metabolic dysfunction.[1]
Learn more about intestinal permeability in our overview article
"Having increased intestinal permeability increases a person’s risk for chronic diseases, many of which may be related to exposure to lipopolysaccharide, an endotoxin present in the cell walls of Gram-negative bacteria."- Dr. Rhonda Patrick Click To Tweet
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Beginning of Q&A
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Q: Can alpha lipoic acid help control blood sugar levels?
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Q: Rhonda's thoughts on Athletic Greens
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Q: Does Urolithin A lose its efficacy when absorbed?
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Q: Do kefir and kombucha counteract each other?
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Q: Rhonda's thoughts on a Consumer Lab email suggesting vitamin C increases risk of death. 1
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Intestinal Permeability presentation 1
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Q: Does a low carb diet elevate ApoB?
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Q: How do you know if you are phenotype A or B?
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Q: Rhonda's pomegranate smoothie (Urolithin A)
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Q: How does "olive leaf powder" differ from "olive leaf extract?
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Q: Is sauna safe after mastectomy due to lymphedema risk? 1
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Q: Are there alternatives to medications for pain management in children?
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Q: Rhonda's thoughts on fasting and keto for long COVID.
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Q: Does sauna have added benefits over simply using that time to exercise? 1
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Q: What do Yamanaka factors do in the human body?
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Q: Rhonda's personal COVID protocol
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Q: Should you load creatine?
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Q: Rhonda's current supplement routine
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Q: Low-Level Laser Therapy for reversing hair loss 1
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Watch previously recorded Q&As with Dr. Rhonda Patrick
Q&A #69 with Dr. Rhonda Patrick (4/5/25)
Dr. Rhonda Patrick covers lithium microdosing, reducing homocysteine, aluminum's link to cancer, and beta-alanine and alpha-lipoic acid supplements.
Q&A #68 with Dr. Rhonda Patrick (3/1/25)
Dr. Rhonda Patrick discusses saturated fats and LDL, luteolin's benefits, glyphosate risks, natural vs. artificial flavors, and black cumin seed effects.
Q&A #67 with Dr. Rhonda Patrick (2/8/25)
Dr. Rhonda Patrick discusses microdosing nicotine, GlyNac benefits, intermittent fasting and hair loss, and cold & flu relief.
Q&A #66 with Dr. Rhonda Patrick (1/4/25)
Dr. Rhonda Patrick discusses GLP-1 agonists, alpha-lipoic acid, ubiquinone vs. ubiquinol, calcium needs, and liquid biopsy cancer screening.
Q&A #65 with Dr. Rhonda Patrick (12/7/24)
Dr. Rhonda Patrick discusses _Akkermansia muciniphila_, vitamin B1's effect on blood sugar, emulsifiers in food, and electrolyte supplements.