Dr. Derya Unutmaz joins Dr. Rhonda Patrick to discuss how AI could extend lifespan, personalize cancer care, and transform medicine within a decade. ... technology genetic engineering diagnostics aging stem cells immune system cancer epigenetics brain
Watch now[toc position='left'] Biological aging clocks are among the most important tools in modern longevity science. They attempt to answer a deceptively simple question: can we measure how fast a person is aging biologically, rather than just counting the number of years they have been alive? The answer is yes—but with important caveats. Epigenetic clocks use patterns of DNA methylation, a chemical tagging system on DNA, to estimate different aspects of aging. Some clocks estimate chronological age. Others predict disease risk, mortality risk, or the current pace of biological aging. This means biol... epigenetics aging telomeres genetics stem cells omega-3 dna damage biomarkers vitamin d senescence multivitamin
Read moreScientists have proposed many ways to measure biological aging, but it is still unclear which markers best predict hard outcomes such as death. A new study tested 14 aging biomarkers side by side to see which were most strongly associated with mortality. The researchers analyzed data from 1,671 adults in the Berlin Aging Study II who were 60 to 80 years old at the start of the study. The biomarkers included inflammatory and hormone-related blood measures, physical function tests, cognitive performance, blood pressure, and DunedinPACE, an epigenetic score that uses chemical tags on DNA measure... aging epigenetics mortality
Read moreDr. Rhonda Patrick and Dr. Charles Brenner discuss NAD precursors, NR versus NMN, NAD IV drips, and what truly boosts NAD for recovery and longevity. ... nad+ pregnancy dna damage aging resveratrol oxidative stress
Watch nowDr. Darren Candow and Dr. Rhonda Patrick discuss the science of creatine for muscle performance and brain health. ... supplements brain aging muscle strength creatine cognition
Watch now[toc position='left'] Introduction Micronutrient deficiencies are widespread. Up to 70% of Americans don’t get enough vitamin D, nearly 50% fall short of their magnesium needs, and 35% have an insufficient intake of calcium. These deficiencies and insufficiencies ravage our health. Inadequate vitamin D increases mortality risk. A magnesium deficiency can accelerate biological aging. Folate deficiency by itself can produce a level of DNA damage that is equivalent to or in excess of an acute exposure to radiation (https://www.cambridge.org/core/journals/nutrition-research-reviews/article/nutrit... vitamin a micronutrients brain vitamin d vitamin c vitamin e vitamin b12 vitamin k mortality aging omega-3 biomarkers multivitamin cognition
Read more[toc position='left'] Introduction Cancer is the second leading cause of death worldwide. Successful treatment hinges on early detection, but conventional screening and diagnostic approaches, often relying on tissue biopsies, come with limitations that hinder their effectiveness. One promising solution is liquid biopsy, a groundbreaking technique that analyzes bodily fluids, such as blood, urine, lymph, and cerebrospinal fluid, for signs of cancer. When these fluids circulate near a tumor, they can acquire shed tumor cells and their components, such as DNA and RNA. Liquid biopsies are innova... cancer biomarkers technology blood test diagnostics
Read more[toc position='left'] Introduction Omega-3 fatty acids are polyunsaturated fats that play critical roles in human health, participating in a wide range of biochemical pathways and processes and modulating the expression of genes throughout the lifespan. Omega-3 fatty acids include plant-derived alpha-linolenic acid (ALA) and marine-derived eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), among others. A growing body of evidence indicates that omega-3 fatty acids may prevent or ameliorate symptoms associated with chronic health conditions such as cardiovascular disease,[ref doi='10.3... cancer depression mortality omega-3 nutrition brain diet aging immune system mental health development intelligence
Read moreDr. Morgan Levine discusses epigenetics and the application of epigenetic aging clocks in quantifying human aging. ... epigenetics cancer aging inflammation senescence
Watch nowBefore you jump right into the timeline here's a few useful links: Tim's blog post for the episode (http://fourhourworkweek.com/2014/06/10/the-tim-ferriss-show-rhonda-patrick-life-extension/), a direct link to the audio file (http://traffic.libsyn.com/timferriss/Episode12_TFS.mp3), and if you haven't already... make sure to signup for the FMF newsletter (see the footer of this page), and grab the FoundMyFitness iPhone app (https://itunes.apple.com/us/app/foundmyfitness-nutrition-science/id859601167). One last note: you may post this anywhere you like!! To make it easier for you to do so... cli...
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