[toc position='left'] Introduction Micronutrient deficiencies are widespread. Up to 70% of Americans don’t get enough vitamin D, nearly 50% fall short of their magnesium needs, and 35% have an insufficient intake of calcium. These deficiencies and insufficiencies ravage our health. Inadequate vitamin D increases mortality risk. A magnesium deficiency can accelerate biological aging. Folate deficiency by itself can produce a level of DNA damage that is equivalent to or in excess of an acute exposure to radiation (https://www.cambridge.org/core/journals/nutrition-research-reviews/article/nutrit... vitamin a micronutrients brain vitamin d vitamin c vitamin e vitamin b12 vitamin k mortality aging omega-3 biomarkers multivitamin cognition
Read more[toc position='left'] Introduction Melatonin isn’t just the “sleep hormone”—it regulates over 500 genes and plays a key role in the body’s antioxidant defenses. As we age, melatonin production declines significantly. By the time a person reaches 50 years old, melatonin levels are 50% of what they were at age 20. By age 80, melatonin production can be ten times lower than in teenagers. (https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2022.888292/full) This reduction in melatonin is linked to changes in sleep patterns, circadian rhythm disruption, and overall healt... melatonin alzheimer's parkinson's sleep circadian rhythm dementia
Read more[toc position='left'] Introduction Cancer is the second leading cause of death worldwide. Successful treatment hinges on early detection, but conventional screening and diagnostic approaches, often relying on tissue biopsies, come with limitations that hinder their effectiveness. One promising solution is liquid biopsy, a groundbreaking technique that analyzes bodily fluids, such as blood, urine, lymph, and cerebrospinal fluid, for signs of cancer. When these fluids circulate near a tumor, they can acquire shed tumor cells and their components, such as DNA and RNA. Liquid biopsies are innova... cancer biomarkers technology blood test diagnostics
Read more[toc position='left'] Introduction Light has profound and diverse effects on the human body, influencing sleep-wake cycles, circadian rhythmicity, mood, and immune function. In recent decades, scientists have begun exploiting the body's responses to light with photobiomodulation, a non-invasive, light-based therapeutic technique. Photobiomodulation employs specific wavelengths of light (measured in nanometers, nm) to stimulate biological processes within cells and tissues, triggering a cascade of physiological responses. A growing body of evidence suggests that photobiomodulation has potential... bone skin brain depression arthritis
Read moreDr. Roger Seheult discusses the roles of vaccines, vitamin D, and heat therapy in the prevention of COVID-19. ... covid-19 vitamin d inflammation virus vaccine
Watch now[toc position='left'] Nicotinamide mononucleotide (NMN) is a precursor molecule for the biosynthesis of nicotinamide adenine dinucleotide, or NAD+, a coenzyme that participates in the production of cellular energy and DNA repair. NAD+ can also be synthesized from other precursors including nicotinamide (NAM, also called niacinamide), nicotinic acid (NA), and nicotinamide riboside (NR), which are often collectively referred to as niacin (vitamin B3) or niacin equivalents.[ref doi='10.12688/f1000research.12120.1'] These precursors are not equally allocated throughout the body; rather, they exhib... aging obesity neurodegeneration exercise cancer dna damage mitochondria nad+ cardiovascular
Read more[toc position='right'] Resveratrol is a natural compound found primarily in the skin of red grapes and the root of Polygonum cuspidatum (also known as Japanese knotweed). It is also present to a lesser degree in peanuts and blueberries. Resveratrol protects the plants in which it is present from fungal attack and the damaging effects of ultraviolet radiation. Originally extracted in the 1940s, resveratrol attracted little interest in terms of human health until 1992 when research suggested that it could mediate some of the cardioprotective effects of red wine.[ref doi='10.3390/molecules220202... exercise resveratrol alzheimer's metabolism cardiovascular
Read more[toc position='left'] Bathing oneself in heat for the purposes of purification, cleansing, and healing is an ancient practice, dating back thousands of years and observed across many cultures. Variations of its use are seen today in the banyas of Russia, the sweat lodges of the American Indians, and, most famously, the saunas of Finland. Sauna use, sometimes referred to as "sauna bathing," is characterized by short-term passive exposure to extreme heat. This exposure elicits mild hyperthermia – an increase in the body's core temperature – that induces a thermoregulatory response involving neu... exercise inflammation sauna aging performance depression bisphenol a heat stress interesting alzheimer's
Read more[toc position='left'] Fasting – the voluntary abstinence from food and drink – is an ancient tradition long believed to be vital to humans' physical and spiritual health. Practiced for millennia by various cultures and religious groups, fasting is now widely appreciated for its beneficial effects on human metabolism and healthspan.[ref doi='10.1194/jlr.P020867'] [ref doi='10.1016/j.cmet.2015.05.012'] [ref doi='10.1093/cdn/nzz044.P08-053-19'] A growing body of evidence suggests that in the absence of ready supplies of glucose and fats from meals, fasting flips a metabolic "switch," liberating f... obesity fasting nutrition diet aging circadian rhythm autophagy
Read moreDr. Rhonda Patrick explains cold shock as hormesis, a beneficial stressor that triggers adaptive processes, promoting resilience. ... cold stress exercise brain cancer obesity performance inflammation immune system mental health muscle
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