Dr. Andrew Huberman discusses the role of dopamine in driving motivation and offers practical tools for enhancing mood and focus. ... brain exercise diet performance alcohol adhd cold stress dopamine supplements
Watch nowBreathwork has shown promise in ameliorating oxidative stress – a driver of many chronic diseases – in healthy people and those with chronic conditions. However, scientists don't fully understand the underlying mechanisms that drive these effects. A recent review found that breathwork promotes the activity of endogenous antioxidant enzymes. Researchers analyzed the findings of 10 randomized controlled trials (519 participants) investigating the effects of breathwork. The studies encompassed a range of breathwork styles and measured various biomarkers, including malondialdehyde, superoxide dis... vitamin c mortality sulforaphane glutathione nitric oxide antioxidant oxidative stress breathing technique
Read moreMorning sickness affects up to 85 percent of pregnant women and is caused by hormonal changes during early pregnancy. Vitamin B6, antihistamines, and some prescription medications are used to treat nausea and vomiting during pregnancy; however, additional treatments that address hormonal imbalances are needed. Findings of a new report show that probiotics reduced nausea and vomiting and improved quality of life in pregnant women. Levels of hormones such as estrogen and progesterone fluctuate throughout pregnancy altering the composition of the gut microbiota and gastrointestinal function. Gut ... probiotics pregnancy
Read moreDr. Bill Harris discusses the roles that omega-3 fatty acids play in cardiovascular and neurocognitive health. ... omega-3 brain aging heart disease biomarkers inflammation immune system pregnancy mortality polyunsaturated fat
Watch nowCurrent dietary guidelines for people living in the United States recommend eating at least five servings of fruits and vegetables daily as part of a healthy eating pattern. Despite these recommendations, evidence indicates that most people consume far less (https://www.cdc.gov/media/releases/2017/p1116-fruit-vegetable-consumption.html). Findings from a recent study indicate that eating two servings of fruit and three servings of vegetables daily reduces the risk of premature death. Fruits and vegetables are rich in vitamins, minerals, complex carbohydrates, and dietary fiber. They also cont... nutrition micronutrients
Read more[toc position='left'] Background Vitamin C, also known as ascorbic acid, is an essential nutrient, widely recognized for its antioxidant properties. These properties arise from its potent redox potential due to its capacity to donate electrons to oxidized molecules. Even in small quantities vitamin C can protect critical molecules in the body such as proteins, lipids, carbohydrates, and nucleic acids (DNA and RNA) from damage by reactive oxygen species, which are generated during normal metabolism, by active immune cells, and through exposure to toxins and pollutants (e.g., certain chemotherap... cancer nutrition exercise interesting
Read more[toc position='left'] Nicotinamide mononucleotide (NMN) is a precursor molecule for the biosynthesis of nicotinamide adenine dinucleotide, or NAD+, a coenzyme that participates in the production of cellular energy and DNA repair. NAD+ can also be synthesized from other precursors including nicotinamide (NAM, also called niacinamide), nicotinic acid (NA), and nicotinamide riboside (NR), which are often collectively referred to as niacin (vitamin B3) or niacin equivalents.[ref doi='10.12688/f1000research.12120.1'] These precursors are not equally allocated throughout the body; rather, they exhib... aging obesity neurodegeneration exercise cancer dna damage mitochondria nad+ cardiovascular
Read more[toc position='left'] Nicotinamide riboside (NR) is a precursor molecule for the biosynthesis of nicotinamide adenine dinucleotide, or NAD+, a coenzyme that participates in the production of cellular energy and repair. Two other NAD+ precursors, nicotinic acid (NA) and nicotinamide (NAM, also called niacinamide), along with nicotinamide riboside, are often collectively referred to as niacin (vitamin B3) or niacin equivalents. These precursors are not equally allocated throughout the body, exhibiting preferential distribution among the blood, brain, gut, and other organs. NAD+ can also be produ... obesity nad+ aging breast milk cardiovascular
Read more[toc position='left'] Nicotinamide adenine dinucleotide (NAD+) is a cofactor (a molecule that assists enzymes in chemical reactions) that plays an essential role in multiple physiological processes, such as energy metabolism, DNA repair, and immune activation. It is necessary for the activity of sirtuins, a class of enzymes involved in longevity, and poly-ADP-ribose polymerases (PARPs), a family of DNA-repair enzymes. Cellular NAD+ production declines with age, however, and its depletion likely drives the onset and progression of multiple age-related conditions such as metabolic dysregulation ... metabolism mitochondria aging dna damage circadian rhythm nad+
Read more[toc position='left'] Sirtuins are highly conserved enzymes that play key roles in healthspan and longevity in multiple organisms. They are linked to the regulation of a variety of metabolic processes, including the release of insulin, mobilization of lipids, response to stress, and modulation of lifespan.[ref doi='10.1016/j.tem.2013.12.001'] [ref doi='10.1016/j.bbapap.2009.11.021'] Sirtuins have been implicated in the pathophysiology of metabolic disorders such as type 2 diabetes; neurological disorders such as Parkinson’s disease; and many other conditions related to aging.[ref doi='10.3389/... aging heart disease circadian rhythm brain cancer inflammation fasting resveratrol
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