[toc position='left'] Introduction Light has profound and diverse effects on the human body, influencing sleep-wake cycles, circadian rhythmicity, mood, and immune function. In recent decades, scientists have begun exploiting the body's responses to light with photobiomodulation, a non-invasive, light-based therapeutic technique. Photobiomodulation employs specific wavelengths of light (measured in nanometers, nm) to stimulate biological processes within cells and tissues, triggering a cascade of physiological responses. A growing body of evidence suggests that photobiomodulation has potential... bone skin brain depression arthritis
Read moreProtein is essential for building and maintaining muscles. Aiming for about 1.2 to 1.6 grams of protein per kilogram of body weight (about 0.5 to 0.7 grams p... ... aliquot nutrition exercise muscle vegetarian protein
Listen now[toc position='left'] Small vessel disease is a condition causing blood vessel dysfunction that occurs with aging and contributes to the development of cardiovascular disease, dementia, and stroke. As a consequence of the profound effects of small vessel disease on the functioning of the brain and blood-brain barrier (/topics/blood-brain-barrier), for the purposes of this article, we will focus predominantly on cerebral aspects of small vessel disease, called cerebral small vessel disease. Small vessel disease in the brain contributes to approximately 50 percent of dementia cases worldwide, in... small vessel disease brain alzheimer's vitamin d omega-3 parkinson's inflammation cardiovascular blood-brain barrier
Read more[toc position='left'] Senescence is a response to stress in which damaged cells terminate normal growth cycles to prevent dysfunctional cells from reproducing. Senescence is a vital cellular process involved in embryonic development, wound healing, and cancer immunity; [ref doi='10.1242/dev.151837'] however, the accumulation of senescent cells is associated with diseases of aging such as cancer, cardiovascular disease, type 2 diabetes, Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, sarcopenia, and glaucoma.[ref doi='10.1016/j.cell.2017.05.015'] [ref doi='10.3390/ijms19102937'] ... neurodegeneration senescence aging
Read more[toc position='left'] Thymic involution is the process by which the thymus shrinks with age and produces fewer T cells, impairing immunity and increasing the risk of infection in older adults. In addition, thymic involution increases the risk of cancer and autoimmunity with age. However, research has identified some of the mechanisms of thymic involution and highlighted possible strategies to improve immunity: By activating PPAR-gamma, a protein that regulates fat metabolism, caloric restriction reduced the rate of thymic involution in mice and increased the number and diversity of circulatin... thymic involution immune system thymus autoimmunity
Read moreDr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session. ... rhonda exercise gut microbiome sleep heart disease diabetes omega-3 fasting pregnancy melatonin vaccine iron gluten covid-19 breast milk wearable technology
Watch nowDr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session. ... rhonda vitamin d exercise parkinson's diet omega-3 vitamin k vegetarian antioxidant protein dairy
Watch nowDr. Satchin Panda discusses the practical aspects of implementing fasting, time-restricted eating, shift work strategies, and more. ... fasting cancer obesity metabolism diabetes circadian rhythm melatonin time-restricted eating
Watch nowScience on refined sugar: mortality, aging, brain function, memory, neuroinflammation, cancer, sex hormones, addiction & more. ... sugar nutrition brain cancer diet aging memory addiction
Listen nowDr. Rhonda Patrick explains cold shock as hormesis, a beneficial stressor that triggers adaptive processes, promoting resilience. ... cold stress exercise brain cancer obesity performance inflammation immune system mental health muscle
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