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      <h3 class="bold">
        [Podcast] Why You Can&#39;t Sleep (and How to Fix It) | Dr. Michael Grandner
      </h3>
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      Dr. Michael Grandner and Dr. Rhonda Patrick explore treatments for insomnia, detecting hidden sleep apnea, and science-backed strategies for better sleep.
...
          <span class="search-tag">sleep</span>
          <span class="search-tag">alcohol</span>
          <span class="search-tag">melatonin</span>
          <span class="search-tag">caffeine</span>
          <span class="search-tag">cbd</span>
          <span class="search-tag">performance</span>
          <span class="search-tag">circadian rhythm</span>
          <span class="search-tag">magnesium</span>
          <span class="search-tag">supplements</span>
          <span class="search-tag">L-Theanine</span>
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        [Topic] Coffee
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      [toc]
Coffee is more than just a morning ritual or a comforting pick-me-up—it&#39;s a scientifically supported pathway to improved health, performance, and longevity. As one of the world&#39;s most widely consumed beverages, coffee has long been celebrated for its energizing properties. However, emerging research now highlights its remarkable potential to extend lifespan, slow biological aging, and reduce the risk of chronic diseases like heart disease, diabetes, and certain cancers.
Coffee reduces the body&#39;s biological age by modulating gene expression and protects against cardiovascular events and n...
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">diabetes</span>
          <span class="search-tag">parkinson&#39;s</span>
          <span class="search-tag">caffeine</span>
          <span class="search-tag">neurodegeneration</span>
          <span class="search-tag">cardiovascular</span>
          <span class="search-tag">metabolism</span>
          <span class="search-tag">coffee</span>
          <span class="search-tag">L-Theanine</span>
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        [Podcast] Dr. Ben Bikman: How To Reverse Insulin Resistance Through Diet, Exercise, &amp; Sleep
      </h3>
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      Dr. Ben Bikman and Rhonda Patrick discuss the primary causes of insulin resistance and how to reverse it in as little as 90 days.
...
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">insulin</span>
          <span class="search-tag">blood sugar</span>
          <span class="search-tag">diabetes</span>
          <span class="search-tag">saturated fat</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">nutrition</span>
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        [Podcast] How To Use Coffee To Live Longer (Full Guide &amp; Research)
      </h3>
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      Dr. Rhonda Patrick discusses coffee&#39;s remarkable ability to slow biological aging, reduce DNA damage, and lower cancer risk. 
...
          <span class="search-tag">coffee</span>
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">caffeine</span>
          <span class="search-tag">dementia</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">cholesterol</span>
          <span class="search-tag">L-Theanine</span>
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        [Topic] Microplastics
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      [toc position=&#39;left&#39;]
Introduction
Microplastics are everywhere: in the food we eat, the water we drink, and even the air we breathe. Imagine consuming the equivalent of a credit card’s worth of plastic every week—just by going about your daily routine. As startling as it may seem, this is the reality we face, exposing our bodies to a hidden threat that’s growing by the day.
What are microplastics? They&#39;re tiny pieces of plastic or other polymer-based materials, ranging from 5 millimeters (~0.2 inches) to as small as 100 nanometers, often called nanoplastics. These tiny particles contain a var...
          <span class="search-tag">environment</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">cardiovascular</span>
          <span class="search-tag">Microplastics</span>
          <span class="search-tag">pollution</span>
          <span class="search-tag">PFAS</span>
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        [Topic] Omega-3 fatty acids
      </h3>
</a>    <p>
      [toc position=&#39;left&#39;]
Introduction
Omega-3 fatty acids are polyunsaturated fats that play critical roles in human health, participating in a wide range of biochemical pathways and processes and modulating the expression of genes throughout the lifespan. Omega-3 fatty acids include plant-derived alpha-linolenic acid (ALA) and marine-derived eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), among others. A growing body of evidence indicates that omega-3 fatty acids may prevent or ameliorate symptoms associated with chronic health conditions such as cardiovascular disease,[ref doi=&#39;10.3...
          <span class="search-tag">cancer</span>
          <span class="search-tag">depression</span>
          <span class="search-tag">mortality</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">nutrition</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">immune system</span>
          <span class="search-tag">mental health</span>
          <span class="search-tag">development</span>
          <span class="search-tag">intelligence</span>
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        [Topic] Sulforaphane
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Sulforaphane is a bioactive compound derived from certain cruciferous vegetables, particularly broccoli (and its sprouts) and red kale. Robust evidence from epidemiological, clinical, rodent, and in vitro studies has demonstrated that sulforaphane exhibits antioxidant and anti-inflammatory properties and may be beneficial against a wide range of chronic and acute diseases, including autism, cancer, metabolic dysfunction, and many others and may ameliorate some of the harmful effects associated with exposure to air pollution.  
Sulforaphane exerts its therapeutic effects t...
          <span class="search-tag">sulforaphane</span>
          <span class="search-tag">cancer</span>
          <span class="search-tag">behavior</span>
          <span class="search-tag">supplements</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">breast cancer</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">autism</span>
          <span class="search-tag">antioxidant</span>
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        [Topic] Lactobacillus reuteri 
      </h3>
</a>    <p>
      [toc position=&#39;left&#39;]
Introduction
Lactobacillus reuteri is a bacterium found in the digestive tracts of mammals, including humans, and in fermented foods. It is a member of the genus Lactobacillus, which comprises most of the bacteria that live on and in the human body. Lactic acid-producing bacteria, such as those in the Lactobacillus genus, are commonly used in probiotic supplements.[ref doi=&#39;10.1016/j.tim.2021.01.003&#39;] Furthermore, some online resources provide step-by-step instructions for at-home bulk production of yogurt with L. reuteri enrichment. (https://drdavisinfinitehealth.com/201...
          <span class="search-tag">gut</span>
          <span class="search-tag">probiotics</span>
          <span class="search-tag">microbiome</span>
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        [Topic] Epigenetic aging clocks
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      [toc position=&#39;left&#39;]
&amp;gt; Epigenetic clocks are a subset of the broader subject of biological aging clocks, which you can read a full write-up on here (/topics/biological-age-clocks).
Epigenetic clocks are predictors of biological age based on alterations in an individual&#39;s DNA methylation profile. Methylations – biochemical processes that modify the activity of a DNA segment without changing its sequence – occur naturally and regulate gene expression to control normal growth and development. With age, the methylation state of various genes may change. These changes are quantifiable and gauge...
          <span class="search-tag">aging</span>
          <span class="search-tag">interesting</span>
          <span class="search-tag">epigenetics</span>
          <span class="search-tag">dna damage</span>
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        [Topic] Metformin
      </h3>
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      [toc position=&#39;left&#39;]
Metformin is a drug commonly used to treat type 2 diabetes. It is the fourth most widely prescribed medication in the United States, with more than 80 million prescriptions for the drug written yearly. Metformin is in a class of drugs called biguanides, which impede liver gluconeogenesis (glucose production in the liver), thereby decreasing glucose uptake in the gut and increasing overall glucose utilization by improving insulin sensitivity in skeletal muscle and fat tissue. Multiple studies demonstrate that metformin reduces fasting blood glucose levels by as much as 3.9...
          <span class="search-tag">exercise</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">diabetes</span>
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