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        [Story] Unhealthy dietary patterns nearly double the prevalence of high-risk plaque in coronary arteries, potentially increasing heart attack risk.
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      Diet plays a critical role in cardiovascular health, influencing disease risk and the biological processes underlying plaque formation in the arteries. However, emerging evidence suggests that not all plaque is equal, with some types more prone to rupture and trigger heart attacks. A recent study found that adults with the least healthy diets were nearly twice as likely to have high-risk plaque in their coronary arteries as those with the healthiest diets. 
Researchers analyzed data from more than 24,000 adults aged 50 to 64, none of whom had been diagnosed with cardiovascular disease. They de...
          <span class="search-tag">cardiovascular</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">heart disease</span>
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        [Podcast] Dr. Ben Bikman: How To Reverse Insulin Resistance Through Diet, Exercise, &amp; Sleep
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      Dr. Ben Bikman and Rhonda Patrick discuss the primary causes of insulin resistance and how to reverse it in as little as 90 days.
...
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">insulin</span>
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        [Podcast] Chris McGlory, PhD, on the Anabolic Potential of Omega-3 Fatty Acids
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      Dr. Chris McGlory discusses muscle protein dynamics, emphasizing how omega-3 helps maintain muscle mass in older adults.
...
          <span class="search-tag">omega-3</span>
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        [Topic] Omega-3 fatty acids
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Introduction
Omega-3 fatty acids are polyunsaturated fats that play critical roles in human health, participating in a wide range of biochemical pathways and processes and modulating the expression of genes throughout the lifespan. Omega-3 fatty acids include plant-derived alpha-linolenic acid (ALA) and marine-derived eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), among others. A growing body of evidence indicates that omega-3 fatty acids may prevent or ameliorate symptoms associated with chronic health conditions such as cardiovascular disease,[ref doi=&#39;10.3...
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        [Story] Microglial interleukin-6 signaling and prostaglandin synthesis may regulate depressive symptoms in neurological disorders. (2021)
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      Microglia and IL-6 drive the negative mood often associated with inflammation.  
People who have certain neurological disorders, such as Alzheimer&#39;s disease, Parkinson&#39;s disease, or stroke, often exhibit low mood. Evidence suggests that inflammation plays a role in the pathogenesis of these neurological disorders and likely influences mood, as well. Findings from a 2021 study suggest that microglia activation drives the low mood often associated with neurological disorders.  
Microglia are the brain’s resident immune cells. They serve an essential role in maintaining brain microenvironment hom...
          <span class="search-tag">brain</span>
          <span class="search-tag">inflammation</span>
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        [Story] Medium chain triglycerides (MCTs) improved cognition in patients with Alzheimer&#39;s disease.
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      Medium-chain triglycerides improve cognitive function in Alzheimer&#39;s disease. 
The brain relies heavily on glucose as its primary fuel, burning as much as 130 grams of glucose per day. However, glucose metabolism in the brain is impaired in Alzheimer&#39;s disease, contributing to many of the disease&#39;s symptoms (https://link.springer.com/article/10.1007/BF03159971). Findings from a recent study demonstrate that ketones derived from medium chain triglyceride metabolism may provide an alternative fuel source for the brain in the setting of Alzheimer&#39;s disease.  
Ketones are molecules produced by the...
          <span class="search-tag">brain</span>
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        [Story] Effects of omega-3 polyunsaturated fatty acids on left ventricular remodeling in chronic heart failure
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      Omega-3 fatty acids improve aspects of heart failure. 
More than 26 million people worldwide currently live with heart failure, a serious condition characterized by diminished capacity of the heart’s ventricles to fill with or eject blood and cardiomyocyte death. Adaptive responses to heart failure induce ventricular remodeling – structural and functional accommodations of the left ventricle that hinder contractility and impair ventricular filling. Findings from a recent systematic review and meta-analysis suggest that omega-3 fatty acids improve aspects of left ventricular remodeling in peopl...
          <span class="search-tag">heart disease</span>
          <span class="search-tag">omega-3</span>
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        [Podcast] Dr. Bill Harris on the Omega-3 Index, Increasing Omega-3 to Improve Longevity &amp; Heart Disease Risk
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      Dr. Bill Harris discusses the roles that omega-3 fatty acids play in cardiovascular and neurocognitive health.
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          <span class="search-tag">omega-3</span>
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        [Story] Omega-3 supplementation improves cognitive performance in cognitively healthy older adults with coronary artery disease.
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      Dementia is a large and growing health concern facing older adults, with approximately 15 to 20 percent of people aged 65 years and older living with mild cognitive impairment. Omega-3 fatty acids have benefits for those with mild cognitive impairment and coronary artery disease, a risk factor for dementia because it restricts blood flow to the brain. Findings of a recent report demonstrate the effects of omega-3 supplementation on cognitive decline in cognitively healthy older adults with coronary artery disease.
The omega-3 fatty acids EPA (eicosapentaenoic acid) and DHA (docosahexaenoic aci...
          <span class="search-tag">brain</span>
          <span class="search-tag">heart disease</span>
          <span class="search-tag">omega-3</span>
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        [Topic] Brain-derived neurotrophic factor (BDNF)
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      [toc position=&#39;left&#39;]
Brain-derived neurotrophic factor, or BDNF, is a growth factor relevant to aging, brain function, behavior, metabolism, energy expenditure, and satiety. BDNF serves as a cell signaling protein, plays vital roles in numerous signaling pathways associated with a variety of disorders ranging from depression, (https://www.foundmyfitness.com/topics/depression) schizophrenia, and addiction to obesity and diabetes, and may serve as a hormone. It is perhaps best known for its influence on the formation, growth, survival, and development of neurons and for its role in mediating th...
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