Psychedelic drugs are drawing renewed interest as possible tools for mental health treatment, but researchers still do not fully understand how they affect the brain. To tackle that question, scientists combined brain-scan data from several countries and analyzed them together to see whether different drugs produce similar changes in the brain. The researchers carried out a mega-analysis, meaning they pooled individual brain-scan data from multiple earlier studies and reanalyzed them together. They focused on resting-state functional magnetic resonance imaging, or resting-state fMRI, which tr... brain psychedelic
Read moreDr. Rhonda Patrick and Brady Holmer discuss training principles from their comprehensive guide. ... exercise aging performance muscle aerobic strength exercise snacks
Watch nowDr. Rhonda Patrick dives into the science of protein and discusses intake requirements, its ties to longevity, and debunks several protein-related myths. ... protein nutrition muscle
Watch now[toc position='left'] Introduction Microplastics are everywhere: in the food we eat, the water we drink, and even the air we breathe. Imagine consuming the equivalent of a credit card’s worth of plastic every week—just by going about your daily routine. As startling as it may seem, this is the reality we face, exposing our bodies to a hidden threat that’s growing by the day. What are microplastics? They're tiny pieces of plastic or other polymer-based materials, ranging from 5 millimeters (~0.2 inches) to as small as 100 nanometers, often called nanoplastics. These tiny particles contain a var... environment brain diet cardiovascular Microplastics pollution PFAS
Read more[toc position='left'] Background [tweetbox text='"Because BHB is involved in such foundational cellular functions as gene regulation, increasing BHB concentrations may be protective against a wide range of diseases."' tweet='"Because BHB is involved in such foundational cellular functions as gene regulation, increasing BHB concentrations may be protective against a wide range of diseases." https://www.foundmyfitness.com/topics/beta-hydroxybutyrate'] Beta-hydroxybutyrate (BHB) is an endogenous (i.e., produced by the body) ketone produced via the breakdown of fats during times of carbohydrate sc... butyrate exercise fasting aging ketosis
Read moreAging causes brain changes that impair cognitive function, even in people who do not have Alzheimer’s disease or dementia. However, lifestyle factors like diet and exercise have significant influence over the rate of cognitive decline. Previous research has shown that exercise improves brain health and cognitive function during aging. A new report details the role of the muscle hormone irisin in the neuroprotective effects of exercise Irisin, a type of myokine, is a hormone secreted from muscle in response to exercise. Previous research has shown that irisin may mediate some of the beneficial ... exercise brain alzheimer's aging hormones neurodegeneration
Read more[toc position='left'] Introduction [tweetbox text='"The beneficial effects of cold exposure may be due to hormesis, a favorable biological response to a mild stressor."' tweet='"The beneficial effects of cold exposure may be due to hormesis, a favorable biological response to a mild stressor." https://www.foundmyfitness.com/topics/cold-exposure-therapy'] Cold exposure to promote good health is an ancient practice, now used to reduce muscle soreness and promote muscle recovery after physical activity. However, regular cold exposure may also improve glucose and lipid metabolism, decrease inflamm... performance cholesterol immune system thermogenesis cold stress brain heart disease diabetes insulin resistance inflammation depression mitochondria neuron blood pressure interesting
Read moreExecutive function refers to a set of cognitive abilities that facilitate control over voluntary behaviors, including attention control, working memory, and cognitive flexibility. While executive functions are critical for complex tasks such as planning, they are also mentally taxing. Without sufficient motivation, people with poor executive function may struggle to meet goals. Researchers report their findings that dopamine signaling is responsible for the effects of Ritalin and other stimulant medications on motivation and executive function. Dopamine is one of the most abundant neurotransmi... brain adhd dopamine
Read more[toc position='left'] Hyperthermia, a state of elevated core body temperature, stresses the body, activating molecular mechanisms that mitigate protein damage and aggregation and promote endogenous antioxidant, repair, and degradation processes. Whole-body hyperthermia is a therapeutic strategy used to treat various medical conditions, including cancer, fibromyalgia, and others.[ref doi='10.1093/annonc/mdf280'][ref doi='10.2147/CIA.S74949'][ref doi='10.3205/000235'] Emerging evidence suggests that whole-body hyperthermia might be useful in treating depression.[ref doi='10.1001/jamapsychiatry.2... sauna cancer depression
Read moreDr. Elissa Epel discusses the mechanisms of healthy aging and the associations between stress, telomere length, addiction, eating, and metabolic health. ... telomeres nutrition diet epigenetics aging stress meditation
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