Dr. Rhonda Patrick examines how one cup of blueberries daily may support vascular function, cognitive aging, metabolic health, and the gut microbiome. ... nutrition exercise brain gut aging microbiome insulin resistance inflammation memory rhonda polyphenol cardiovascular
Watch now[toc position='left'] Biological aging clocks are among the most important tools in modern longevity science. They attempt to answer a deceptively simple question: can we measure how fast a person is aging biologically, rather than just counting the number of years they have been alive? The answer is yes—but with important caveats. Epigenetic clocks use patterns of DNA methylation, a chemical tagging system on DNA, to estimate different aspects of aging. Some clocks estimate chronological age. Others predict disease risk, mortality risk, or the current pace of biological aging. This means biol... epigenetics aging telomeres genetics stem cells omega-3 dna damage biomarkers vitamin d senescence multivitamin
Read moreDr. Luc van Loon discusses optimal protein intake & distribution strategies for stimulating muscle protein synthesis. ... protein muscle cold stress supplements
Watch now[toc position='left'] Introduction Light has profound and diverse effects on the human body, influencing sleep-wake cycles, circadian rhythmicity, mood, and immune function. In recent decades, scientists have begun exploiting the body's responses to light with photobiomodulation, a non-invasive, light-based therapeutic technique. Photobiomodulation employs specific wavelengths of light (measured in nanometers, nm) to stimulate biological processes within cells and tissues, triggering a cascade of physiological responses. A growing body of evidence suggests that photobiomodulation has potential... bone skin brain depression arthritis
Read more[toc position='left'] The blood-brain barrier comprises various membranes that separate the central nervous system (CNS) and the peripheral circulatory system. The purpose of this barrier is to allow the passage of nutrients and cell signals from the bloodstream to nerves and supporting cells in the CNS while excluding harmful substances. Genetic predispositions, environmental exposures, and aging may weaken the integrity of this barrier, allowing endotoxins and inflammatory immune cells to infiltrate the brain, contributing to accelerated brain aging and the risk of neurodegenerative diseases... omega-3 immune system blood-brain barrier brain alzheimer's gut obesity
Read more[toc position='left'] Carotenoids are orange/yellow pigments in various foods, such as carrots, pumpkins, avocados, and salmon. While carotenoids are a highly diverse group of organic pigments, with over 1,100 known carotenoids [ref doi='10.1093/database/bax004'], this overview will focus on lutein and zeaxanthin, which are of particular interest due to their notable roles in eye and brain health. Carotenoids are one of the most common classes of bioactive compounds found in plants, along with alkaloids (e.g., berberine), organosulfur compounds (e.g., sulforaphane), and polyphenols (e.g., anth... carotenoids cholesterol eyes antioxidant
Read moreDr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session. ... rhonda exercise gut microbiome sleep heart disease diabetes omega-3 fasting pregnancy melatonin vaccine iron gluten covid-19 breast milk wearable technology
Watch now[toc position='left'] Metformin is a drug commonly used to treat type 2 diabetes. It is the fourth most widely prescribed medication in the United States, with more than 80 million prescriptions for the drug written yearly. Metformin is in a class of drugs called biguanides, which impede liver gluconeogenesis (glucose production in the liver), thereby decreasing glucose uptake in the gut and increasing overall glucose utilization by improving insulin sensitivity in skeletal muscle and fat tissue. Multiple studies demonstrate that metformin reduces fasting blood glucose levels by as much as 3.9... exercise aging diabetes
Read more[toc position='left'] Fasting – the voluntary abstinence from food and drink – is an ancient tradition long believed to be vital to humans' physical and spiritual health. Practiced for millennia by various cultures and religious groups, fasting is now widely appreciated for its beneficial effects on human metabolism and healthspan.[ref doi='10.1194/jlr.P020867'] [ref doi='10.1016/j.cmet.2015.05.012'] [ref doi='10.1093/cdn/nzz044.P08-053-19'] A growing body of evidence suggests that in the absence of ready supplies of glucose and fats from meals, fasting flips a metabolic "switch," liberating f... obesity fasting nutrition diet aging circadian rhythm autophagy
Read moreDrs. Erica and Justin Sonnenburg both research the interaction between diet and the trillions of bacteria in the gut. ... microbiome nutrition diet probiotics fiber
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