Dr. Ben Bikman and Rhonda Patrick discuss the primary causes of insulin resistance and how to reverse it in as little as 90 days. ... insulin resistance insulin blood sugar diabetes saturated fat diet nutrition
Watch nowDr. Andy Galpin & Dr. Rhonda Patrick discuss nutrition, supplement, and recovery strategies for improving exercise performance. ... exercise supplements nutrition sleep performance omega-3 vitamin e heat stress cold stress iron protein
Watch now[toc position='left'] Creatine (https://www.foundmyfitness.com/topics/creatine) is a naturally occurring compound that is critical in storing and releasing cellular energy. It also participates in many biological processes driving pregnancy outcomes, maintaining bone mineral density and muscle mass in older adults, improving neurological function, and aiding the immune system to fight cancer. Creatine is best known for its widespread use as a dietary supplement to enhance physical performance. Creatine, phosphocreatine, creatine transporters, and creatine kinase enzymes are expressed in the en... cardiovascular heart disease
Read moreDr. Rhonda Patrick explains how HIIT, circadian-timed eating, and quality sleep improve metabolic health and reduce chronic disease risk. ... metabolism exercise sleep time-restricted eating
Watch now[toc position='left'] Consider a drug capable of reversing the effects of aging on the heart, restoring its youthful function. That's what researchers observed when they gave dogs rapamycin—a drug traditionally used to treat certain cancers and prevent organ transplant rejection. The findings were striking: The dogs exhibited marked improvements in heart function, effectively reversing the age-related changes typically seen in aging. While these findings are remarkable, they add to a growing body of research indicating that rapamycin might enhance healthspan and promote longevity in various sp... aging autophagy metabolism immune system cancer drug
Read more[toc position='left'] Introduction Magnesium is an essential dietary mineral. It plays critical roles in myriad physiological processes, serving as a cofactor to more than 300 enzymes in the human body and maintaining the integrity of cellular structures and DNA. Magnesium deficiency is widespread, affecting more than half of people in the U.S. and increasing the risk of many chronic conditions, including cancer, metabolic disorders, and neurodegenerative diseases. At a glance, magnesium participates in: Enzymatic reactions, serving as a cofactor for more than 300 enzymes involved in variou... magnesium brain nutrition supplements micronutrients
Read more[toc position='left'] Creatine is a naturally occurring compound that is critical in storing and releasing cellular energy. It also participates in many biological processes driving pregnancy outcomes, maintaining bone mineral density and muscle mass in older adults, improving neurological function, and aiding the immune system to fight cancer. Creatine is best known for its widespread use as a dietary supplement to enhance physical performance. Creatine uptake, synthesis, storage, and supplementation Creatine uptake Creatine can be supplied exogenously (from dietary or supplemental sources) ... metabolism neurodegeneration nutrition brain aging depression pregnancy
Read more[toc position='left'] Nicotinamide adenine dinucleotide (NAD+) is a cofactor (a molecule that assists enzymes in chemical reactions) that plays an essential role in multiple physiological processes, such as energy metabolism, DNA repair, and immune activation. It is necessary for the activity of sirtuins, a class of enzymes involved in longevity, and poly-ADP-ribose polymerases (PARPs), a family of DNA-repair enzymes. Cellular NAD+ production declines with age, however, and its depletion likely drives the onset and progression of multiple age-related conditions such as metabolic dysregulation ... metabolism mitochondria aging dna damage circadian rhythm nad+
Read more[toc position='left'] Sirtuins are highly conserved enzymes that play key roles in healthspan and longevity in multiple organisms. They are linked to the regulation of a variety of metabolic processes, including the release of insulin, mobilization of lipids, response to stress, and modulation of lifespan.[ref doi='10.1016/j.tem.2013.12.001'] [ref doi='10.1016/j.bbapap.2009.11.021'] Sirtuins have been implicated in the pathophysiology of metabolic disorders such as type 2 diabetes; neurological disorders such as Parkinson’s disease; and many other conditions related to aging.[ref doi='10.3389/... aging heart disease circadian rhythm brain cancer inflammation fasting resveratrol
Read moreSupplementary links: Academic paper this was originally attached to (http://jem.rupress.org/content/early/2014/05/27/jem.20132336.abstract). Additional Video 2 (http://rup-movie.glencoesoftware.com/video/10.1084/jem.20132336/video-2) Additional Video 3 (http://rup-movie.glencoesoftware.com/video/10.1084/jem.20132336/video-3) Additional Video 4 (http://rup-movie.glencoesoftware.com/video/10.1084/jem.20132336/video-4) Additional Video 5 (http://rup-movie.glencoesoftware.com/video/10.1084/jem.20132336/video-5) ... bone
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