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        [Podcast] How to Build Muscle With Plant-Based Protein
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      Dr. Luc van Loon explains how protein dose, amino acids, digestibility, and processing shape muscle growth on plant-based diets.
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          <span class="search-tag">nutrition</span>
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        [Podcast] Dr. Luc van Loon: Optimizing Protein Intake &amp; Distribution for Muscle Growth
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      Dr. Luc van Loon discusses optimal protein intake &amp;amp; distribution strategies for stimulating muscle protein synthesis.
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        [Podcast] Aliquot #18: The dual nature of IGF-1: Striking a balance for optimal health
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      Insulin-like growth factor-1, or IGF-1 for short, is a protein that plays critical roles in major growth pathways in the human body. It influences nearly eve...
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        [Story] BDNF variant may mediate degree of brain benefits from exercise.
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      Exercise improves cognitive function and reduces the risk neurodegenerative diseases such as Alzheimer&#39;s disease. Some of these benefits are mediated by brain-derived neurotrophic factor (BDNF). Findings from a 2012 study showed that regular exercise improved cognitive function and increased BDNF levels, but a genetic variant in BDNF influenced the degree of these effects. 
BDNF is a protein that acts on neurons in the central and peripheral nervous systems. A single-nucleotide polymorphism (SNP) in the gene that encodes BDNF causes a substitution of the amino acid valine (Val) by methionine (...
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        [Story] Carriers of a common BDNF genetic variant demonstrate more rapid decline from Alzheimer&#39;s disease.
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      BDNF plays critical roles in many aspects of cognitive function, including learning and memory formation. A single-nucleotide polymorphism (SNP) in the gene that encodes BDNF causes a substitution of the amino acid valine (Val) by methionine (Met) in a specific region of the DNA where the gene is located. Evidence suggests that carrying the Met allele (Met/Met or Val/Met genotype) is associated with lower BDNF expression. (https://pubmed.ncbi.nlm.nih.gov/12553913/). A 2017 study found that amyloid-beta burden impaired BDNF-related learning and memory. 
Amyloid-beta is a toxic 42-amino acid pep...
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        [Story] Women with a BDNF genetic variant experience fewer negative cognitive effects during chemotherapy.
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      Chemotherapy-associated cognitive impairment is a side-effect of chemotherapy in which people experience difficulties with concentration, decision making, and memory. Findings from a 2015 study suggest that women with a BDNF gene variation experience fewer cognitive problems during chemotherapy compared to those without this variation.
BDNF is a growth factor that is involved in the growth and repair of neurons. BDNF is expressed in the prefrontal cortex and hippocampus regions of the brain, which are involved in executive function, learning, and memory. A common variation in the BDNF gene cal...
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        [Story] BDNF genetic variant influences response to exposure therapy among people with PTSD.
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      Exposure therapy is a type of cognitive behavioral therapy commonly used to treat people with posttraumatic stress disorder (PTSD) (https://www.apa.org/ptsd-guideline/patients-and-families/exposure-therapy). Some evidence suggests that BDNF mediates the response to exposure therapy, which can vary among people. A 2013 study demonstrated that genetic differences in BDNF expression influences how well a person responds to exposure therapy. 
A single-nucleotide polymorphism (SNP) in the region of the DNA that encodes BDNF causes a substitution of the amino acid valine (Val) by methionine (Met) in...
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        [Topic] Zinc
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Background
Zinc is an essential nutrient that participates in numerous biological processes and modulates the activity of more than 300 enzymes and 2,000 transcription factors.[ref doi=&#39;10.1136/bmj.326.7386.409&#39;] First identified for its influence on growth and development, zinc is now understood to play critical roles in immune function, protein synthesis, wound healing, DNA synthesis, and cell division. 
History
The importance of zinc in the human diet first became apparent in the early 1960s, after a patient with a rare syndrome presented to Dr. Ananda Prasad, a physic...
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        [Podcast] Growth hormone defect protects against cancer, diabetes, and cognitive decline | Valter Longo
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      Dr. Valter Longo explains how certain macronutrients influence the insulin/IGF-1/growth hormone axis to modulate aging in many cell types. 
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