Dr. Rhonda Patrick reviews how exercise, sleep, stress management, diet, and key nutrients can support immune function with age. ... nutrition exercise aging sleep immune system stress rhonda heat stress cold stress supplements
Watch nowDr. Rhonda Patrick reviews how coffee relates to cancer risk, DNA strand breaks, and the gut microbiome. ... coffee cancer gut microbiome dna damage polyphenol nrf2
Watch now[toc] Psilocybin, a naturally occurring psychedelic compound, is found in over 200 species of mushrooms, commonly known as "magic mushrooms," with a long history of use in indigenous cultures for religious, healing, and divinatory purposes, particularly in regions like Mexico and South America. Chemically, psilocybin is rapidly metabolized into psilocin, which acts as a serotonin 2A receptor agonist, producing profound alterations in consciousness. In clinical settings, psilocybin is administered as a synthesized compound under tightly controlled conditions, involving extensive participant pre... serotonin psychedelic depression anxiety mental health aging
Read more[toc position='left'] Consider a drug capable of reversing the effects of aging on the heart, restoring its youthful function. That's what researchers observed when they gave dogs rapamycin—a drug traditionally used to treat certain cancers and prevent organ transplant rejection. The findings were striking: The dogs exhibited marked improvements in heart function, effectively reversing the age-related changes typically seen in aging. While these findings are remarkable, they add to a growing body of research indicating that rapamycin might enhance healthspan and promote longevity in various sp... aging autophagy metabolism immune system cancer drug
Read more[toc position='left'] Background [tweetbox text='"Because BHB is involved in such foundational cellular functions as gene regulation, increasing BHB concentrations may be protective against a wide range of diseases."' tweet='"Because BHB is involved in such foundational cellular functions as gene regulation, increasing BHB concentrations may be protective against a wide range of diseases." https://www.foundmyfitness.com/topics/beta-hydroxybutyrate'] Beta-hydroxybutyrate (BHB) is an endogenous (i.e., produced by the body) ketone produced via the breakdown of fats during times of carbohydrate sc... butyrate exercise fasting aging ketosis
Read more[toc position='left'] Background Berberine is an alkaloid compound present in the roots, stems, rhizomes, and bark of a variety of plants, including Californian poppy, goldenseal, cork tree, Chinese goldthread, Oregon grape, and several plants in the Berberis genus. It is also widely available as a dietary supplement. Berberine has a long history of use in the ancient and traditional medicine systems of India, China, and Persia. Research demonstrates that berberine may exert pharmacological effects against certain chronic health conditions such as cardiovascular disease, gastrointestinal disor... exercise brain parkinson's depression aging diabetes heart disease fatty liver
Read more[toc position='left'] Sirtuins are highly conserved enzymes that play key roles in healthspan and longevity in multiple organisms. They are linked to the regulation of a variety of metabolic processes, including the release of insulin, mobilization of lipids, response to stress, and modulation of lifespan.[ref doi='10.1016/j.tem.2013.12.001'] [ref doi='10.1016/j.bbapap.2009.11.021'] Sirtuins have been implicated in the pathophysiology of metabolic disorders such as type 2 diabetes; neurological disorders such as Parkinson’s disease; and many other conditions related to aging.[ref doi='10.3389/... aging heart disease circadian rhythm brain cancer inflammation fasting resveratrol
Read more[toc position='right'] Resveratrol is a natural compound found primarily in the skin of red grapes and the root of Polygonum cuspidatum (also known as Japanese knotweed). It is also present to a lesser degree in peanuts and blueberries. Resveratrol protects the plants in which it is present from fungal attack and the damaging effects of ultraviolet radiation. Originally extracted in the 1940s, resveratrol attracted little interest in terms of human health until 1992 when research suggested that it could mediate some of the cardioprotective effects of red wine.[ref doi='10.3390/molecules220202... exercise resveratrol alzheimer's metabolism cardiovascular
Read moreFOXO proteins are members of the FOX family of highly conserved transcriptional regulators. They play essential roles in human lifespan and healthy aging, influenced by environmental and genetic factors. The genetic contribution to lifespan and aging increases with time, suggesting that people who live long lives might carry so-called "protective genes." Run the longevity report to learn more about genetic polymorphisms influencing the expression of FOXO (/genetics) Background FOX proteins are named for a gene found in fruit flies that causes the insects to have forked structures on their head... aging fasting nutrition diet
Read moreScience on refined sugar: mortality, aging, brain function, memory, neuroinflammation, cancer, sex hormones, addiction & more. ... sugar nutrition brain cancer diet aging memory addiction
Listen now