[toc position='left'] Biological aging clocks are among the most important tools in modern longevity science. They attempt to answer a deceptively simple question: can we measure how fast a person is aging biologically, rather than just counting the number of years they have been alive? The answer is yes—but with important caveats. Epigenetic clocks use patterns of DNA methylation, a chemical tagging system on DNA, to estimate different aspects of aging. Some clocks estimate chronological age. Others predict disease risk, mortality risk, or the current pace of biological aging. This means biol... epigenetics aging telomeres genetics stem cells omega-3 dna damage biomarkers vitamin d senescence multivitamin
Read morePrediabetes, a condition in which markers of blood sugar regulation are higher than normal but not yet in the diabetic range, is typically treated by focusing on weight loss. However, many people struggle to lose weight or keep it off. A new study examined whether people with prediabetes could return to normal blood sugar levels without losing weight, and whether this change affected their future risk of type 2 diabetes. The researchers analyzed data from a previous large German lifestyle intervention study, focusing on 234 adults with overweight or obesity (BMI around 30) who maintained or e... diabetes metabolism visceral fat
Read moreLong hours of sitting in office jobs contribute to metabolic dysfunction, but practical and evidence-based strategies to counter this within daily routines remain limited. In a new randomized trial, researchers tested whether brief bodyweight exercises built into each work hour could improve metabolic health over 12 weeks. The study enrolled 86 adults aged 25–55 from three desk-based workplaces who sat more than six hours per day and reported fewer than 150 minutes per week of moderate-to-vigorous physical activity (MVPA). Researchers focused on fasting blood glucose, blood glucose two hours ... blood pressure blood sugar cholesterol exercise metabolism
Read moreStatins are the first line of defense against high LDL cholesterol, but increasing the dose for better results often leads to more side effects. A team of researchers wanted to know whether adding a simple fiber supplement could make a standard statin dose more effective. To find out, they analyzed data from three clinical trials that tested psyllium taken with a statin versus the same statin taken alone. The studies included 204 adults, mostly with high LDL cholesterol, who received treatment for 4 to 12 weeks. Statins used included simvastatin, atorvastatin, or lovastatin, at doses of 10 to ... cholesterol fiber
Read moreDr. Rhonda Patrick explains how creatine supports muscle and brain energy and reviews high-dose research during acute sleep deprivation. ... sleep brain supplements creatine cognition performance
Watch nowPreadolescence is a critical stage for both physical growth and emotional well-being, and new findings highlight how body fat, lean mass, and fitness may connect with anxiety and depression. The study included 207 children aged 8 to 11 from the Greater Boston area, each completing a single lab visit. During this visit, their body composition was measured with dual-energy X-ray absorptiometry (DXA), which provided detailed readings of overall body fat, lean mass, and visceral fat (fat stored around internal organs). To assess fitness, each child performed a treadmill test with respiratory mon... anxiety depression development exercise fat inflammation nutrition obesity
Read moreCreatine plays a key role in maintaining cellular energy balance, and evidence suggests it can help the brain... ... stress aging concussion neurodegeneration brain depression aliquot
Listen nowDrs. Rhonda Patrick and Darren Candow discuss creatine dosing for brain energy, aging, sleep loss, and mental fatigue. ... brain sleep supplements aging creatine cognition
Watch nowDr. Darren Candow and Dr. Rhonda Patrick discuss the science of creatine for muscle performance and brain health. ... supplements brain aging muscle strength creatine cognition
Watch now[toc position='left'] Nutrition in the first year of life is crucial to an infant's development and lifelong health. Early nutritional deficits are intrinsically linked to impaired mental and physical growth. Consequently, the risk of developing metabolic and cardiovascular diseases such as obesity, diabetes, and hypertension in childhood and later life is likely determined by early feeding and nutritional status. Breastfeeding is the biologically superior way to feed an infant. The American Academy of Pediatrics recommends exclusive breastfeeding for the first six months of an infant's life ... cancer breast cancer circadian rhythm nutrition brain microbiome heart disease diabetes inflammation alcohol stem cells immune system development intelligence
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