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    <a data-turbo="false" href="/episodes/how-to-improve-sleep-continuity-and-depth">
      <h3 class="bold">
        [Podcast] How to Improve Sleep Continuity and Depth
      </h3>
</a>    <p>
      Dr. Rhonda Patrick shares sleep strategies involving light, timing, temperature, routines, and carefully selected supplements.
...
          <span class="search-tag">sleep</span>
          <span class="search-tag">circadian rhythm</span>
          <span class="search-tag">melatonin</span>
          <span class="search-tag">magnesium</span>
          <span class="search-tag">rhonda</span>
          <span class="search-tag">supplements</span>
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        [Podcast] Q&amp;A #78: How to Raise Healthy Eaters—Nutrition for Active Children Ages 6–12
      </h3>
</a>    <p>
      Dr. Rhonda Patrick discusses child nutrition, osteoporosis, cholesterol-lowering supplements, her skincare routine, and fasting versus prioritizing protein.
...
          <span class="search-tag">rhonda</span>
          <span class="search-tag">fasting</span>
          <span class="search-tag">cholesterol</span>
          <span class="search-tag">autophagy</span>
          <span class="search-tag">bone</span>
          <span class="search-tag">supplements</span>
          <span class="search-tag">nutrition</span>
          <span class="search-tag">creatine</span>
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        [Podcast] Q&amp;A #71: Does Neu5Gc in Red Meat Raise Cancer Risk?—Plus Cholesterol Drugs &amp; Diabetes Risk
      </h3>
</a>    <p>
      Dr. Rhonda Patrick discusses her supplement routine, Neu5Gc risks, Repatha and diabetes, heat stress, osteoporosis in men, and plyometrics.
...
          <span class="search-tag">heat stress</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">probiotics</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">cholesterol</span>
          <span class="search-tag">sauna</span>
          <span class="search-tag">bone</span>
          <span class="search-tag">nrf2</span>
          <span class="search-tag">supplements</span>
          <span class="search-tag">rhonda</span>
          <span class="search-tag">Ubiquinol</span>
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      <h3 class="bold">
        [Story] Drop set training, a resistance method involving exercising to muscle failure at decreasing weights, promotes muscle growth as effectively as traditional workouts but in less time.
      </h3>
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      Drop sets are a popular resistance-training method for promoting muscle growth. They involve performing an exercise to muscle failure at a given weight, then reducing the weight and immediately continuing to muscle failure again. A recent review and meta-analysis found that drop sets promote muscle hypertrophy as effectively as traditional training but require less time commitment.
Researchers analyzed the findings of six studies investigating the effects of drop-set training on muscle hypertrophy. They found that both drop-set and traditional training groups experienced marked muscle growth a...
          <span class="search-tag">exercise</span>
          <span class="search-tag">muscle</span>
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      <h3 class="bold">
        [Podcast] How Dr. Rhonda Patrick Uses Sauna and Heat
      </h3>
</a>    <p>
      Dr. Rhonda Patrick shares her sauna routine, heat-adaptation approach, hydration practices, and caution when moving from heat to cold.
...
          <span class="search-tag">sauna</span>
          <span class="search-tag">cardiovascular</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">heat stress</span>
          <span class="search-tag">cold stress</span>
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        [Story] Bilophila genus bacteria metabolize precursor to TMAO into alternate product, possibly mitigating some risk of cardiovascular disease
      </h3>
</a>    <p>
      From the article:
&amp;gt; &quot;The connection between TMAO and cardiovascular disease has tended to focus the conversation on how animal-based diets cause negative health consequences,&quot; said Veronika Kivenson, the study&#39;s lead author and a postdoctoral fellow in the OSU College of Science. &quot;But in analyzing data from foundational gut microbiome studies, we uncovered evidence that one type of bacteria associated with meat consumption can take the TMA, as well as precursors to TMA, and metabolize them without producing any TMAO. That means those bacteria are in effect severing a key link in the cardiov...
          <span class="search-tag">gut</span>
          <span class="search-tag">microbiome</span>
          <span class="search-tag">heart disease</span>
          <span class="search-tag">cardiovascular</span>
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        [Topic] Carotenoids
      </h3>
</a>    <p>
      [toc position=&#39;left&#39;]
Carotenoids are orange/yellow pigments in various foods, such as carrots, pumpkins, avocados, and salmon. While carotenoids are a highly diverse group of organic pigments, with over 1,100 known carotenoids [ref doi=&#39;10.1093/database/bax004&#39;], this overview will focus on lutein and zeaxanthin, which are of particular interest due to their notable roles in eye and brain health.
Carotenoids are one of the most common classes of bioactive compounds found in plants, along with alkaloids (e.g., berberine), organosulfur compounds (e.g., sulforaphane), and polyphenols (e.g., anth...
          <span class="search-tag">carotenoids</span>
          <span class="search-tag">cholesterol</span>
          <span class="search-tag">eyes</span>
          <span class="search-tag">antioxidant</span>
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        [Story] Randomized controlled trial finds aerobic exercise alone or aerobic exercise plus dietary changes improved executive function in older individuals.
      </h3>
</a>    <p>
      Randomized controlled trial finds aerobic exercise alone or aerobic exercise plus dietary changes improved executive function in older individuals after 6 months. The exercise plus dietary changes group had executive function scores corresponding to a 9-year improvement.
The aerobic exercise consisted of walking, jogging, or cycling for 45 minutes, three times per week. The aerobic exercise alone improved executive function.
The dietary changes included a DASH diet and did not improve executive function alone but in combination with exercise, it improved executive function better than exercise...
          <span class="search-tag">exercise</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">aerobic</span>
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        [Story] Diet high in saturated fat &amp; low in refined sugar/processed foods improved triglycerides, insulin/blood sugar &amp; more.
      </h3>
</a>    <p>
      This may be further evidence that it is the processed foods and refined sugar that can make saturated fat dangerous but in the absence of that junk food saturated fat is not bad (however, other genetic factors can also be important here). Many of the studies out there do not differentiate between a person eating a low refined-carb/high-saturated fat diet and the standard American diet.
...
          <span class="search-tag">heart disease</span>
          <span class="search-tag">cholesterol</span>
          <span class="search-tag">fat</span>
          <span class="search-tag">insulin</span>
          <span class="search-tag">saturated fat</span>
          <span class="search-tag">triglycerides</span>
          <span class="search-tag">blood sugar</span>
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        [Story] Antigen-specific immunotherapy: proteins like those that cause multiple sclerosis synthesized exogenously &amp; injected create self-tolerance
      </h3>
</a>    <p>
      FTA:
&amp;gt; [...] by synthesising proteins from the [myelin] sheaths in a lab, and then injecting them into the blood stream at increasing doses, the body begins to learn that they are safe.
&amp;gt; [...] “In allergies the immune system mounts a response to something like pollen or nuts because it wrongly believes they will harm the body.
&amp;gt; “But in autoimmune diseases the immune systems sees little protein fragments in your own tissue as foreign invaders and starts attacking them.
&amp;gt; “What we have found is that by synthesising those proteins in a soluble form we can desensitise the immune syst...
          <span class="search-tag">immune system</span>
          <span class="search-tag">multiple sclerosis</span>
          <span class="search-tag">protein</span>
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