Dr. Michael Grandner and Dr. Rhonda Patrick explore treatments for insomnia, detecting hidden sleep apnea, and science-backed strategies for better sleep. ... sleep alcohol melatonin caffeine cbd performance circadian rhythm magnesium supplements L-Theanine
Watch nowDr. Rhonda Patrick discusses coffee's remarkable ability to slow biological aging, reduce DNA damage, and lower cancer risk. ... coffee alzheimer's caffeine dementia brain diet cholesterol L-Theanine
Watch nowDr. Rhonda Patrick discusses Akkermansia muciniphila, vitamin B1's effect on blood sugar, emulsifiers in food, and electrolyte supplements. ... rhonda exercise diet microbiome micronutrients sauna blood sugar supplements
Watch nowDr. Andrew Huberman discusses the role of dopamine in driving motivation and offers practical tools for enhancing mood and focus. ... brain exercise diet performance alcohol adhd cold stress dopamine supplements
Watch nowDr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session. ... rhonda vitamin d aging coffee curcumin caffeine bone calcium polyphenol supplements menopause
Watch nowDr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session. ... rhonda vitamin d exercise sleep omega-3 fasting pregnancy adhd muscle autophagy resveratrol sulforaphane metformin supplements ketogenic diet wearable technology
Watch now[toc position='left'] Metformin is a drug commonly used to treat type 2 diabetes. It is the fourth most widely prescribed medication in the United States, with more than 80 million prescriptions for the drug written yearly. Metformin is in a class of drugs called biguanides, which impede liver gluconeogenesis (glucose production in the liver), thereby decreasing glucose uptake in the gut and increasing overall glucose utilization by improving insulin sensitivity in skeletal muscle and fat tissue. Multiple studies demonstrate that metformin reduces fasting blood glucose levels by as much as 3.9... exercise aging diabetes
Read more[toc position='left'] Nicotinamide adenine dinucleotide (NAD+) is a cofactor (a molecule that assists enzymes in chemical reactions) that plays an essential role in multiple physiological processes, such as energy metabolism, DNA repair, and immune activation. It is necessary for the activity of sirtuins, a class of enzymes involved in longevity, and poly-ADP-ribose polymerases (PARPs), a family of DNA-repair enzymes. Cellular NAD+ production declines with age, however, and its depletion likely drives the onset and progression of multiple age-related conditions such as metabolic dysregulation ... metabolism mitochondria aging dna damage circadian rhythm nad+
Read more[toc position='left'] Sirtuins are highly conserved enzymes that play key roles in healthspan and longevity in multiple organisms. They are linked to the regulation of a variety of metabolic processes, including the release of insulin, mobilization of lipids, response to stress, and modulation of lifespan.[ref doi='10.1016/j.tem.2013.12.001'] [ref doi='10.1016/j.bbapap.2009.11.021'] Sirtuins have been implicated in the pathophysiology of metabolic disorders such as type 2 diabetes; neurological disorders such as Parkinson’s disease; and many other conditions related to aging.[ref doi='10.3389/... aging heart disease circadian rhythm brain cancer inflammation fasting resveratrol
Read moreNutrigenomics examines how genetic variation influences micronutrient absorption and metabolism, and the biological consequences of these interactions. ... epigenetics vitamin d nutrition exercise aging metabolism sleep diabetes telomeres dna damage stem cells stress melatonin vitamin e genetics 23andme heat stress autophagy autism folate sauna antioxidant
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