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    <a data-turbo="false" href="/episodes/how-to-train">
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        [Podcast] How to Train According to the Experts
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      Dr. Rhonda Patrick and Brady Holmer discuss training principles from their comprehensive guide.
...
          <span class="search-tag">exercise</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">performance</span>
          <span class="search-tag">muscle</span>
          <span class="search-tag">aerobic</span>
          <span class="search-tag">strength</span>
          <span class="search-tag">exercise snacks</span>
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        [Topic] Magnesium
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Introduction
Magnesium is an essential dietary mineral. It plays critical roles in myriad physiological processes, serving as a cofactor to more than 300 enzymes in the human body and maintaining the integrity of cellular structures and DNA. Magnesium deficiency is widespread, affecting more than half of people in the U.S. and increasing the risk of many chronic conditions, including cancer, metabolic disorders, and neurodegenerative diseases.  
At a glance, magnesium participates in: 
Enzymatic reactions, serving as a cofactor for more than 300 enzymes involved in variou...
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          <span class="search-tag">micronutrients</span>
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        [Topic] Aerobic exercise
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Aerobic exercise can be defined as physical activity that increases aerobic metabolism, meaning energy-generating processes that require oxygen. Common examples of aerobic exercises are walking, running, swimming, dancing, and other activities that increase heart rate and breathing. Exercise elicits a wide range of physiological changes in the body that improve cardiovascular, neurological, and metabolic health. 
Current physical activity guidelines from the United States Department of Health and Human Services (https://health.gov/our-work/nutrition-physical-activity/phys...
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        [Topic] Polyphenols
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Polyphenols comprise a group of antioxidant compounds found in a variety of plants consumed as foods and beverages. Polyphenols are one of the most common classes of bioactive compounds found in plants, along with alkaloids (e.g., berberine (https://www.foundmyfitness.com/topics/berberine)), organosulfur compounds (e.g., sulforaphane), and terpenoids (e.g., beta carotene). A growing body of evidence suggests that polyphenols have disease-fighting properties, although the evidence to support these claims varies in quality.
Research has demonstrated some degree of efficacy ...
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        [Topic] Brain-derived neurotrophic factor (BDNF)
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Brain-derived neurotrophic factor, or BDNF, is a growth factor relevant to aging, brain function, behavior, metabolism, energy expenditure, and satiety. BDNF serves as a cell signaling protein, plays vital roles in numerous signaling pathways associated with a variety of disorders ranging from depression, (https://www.foundmyfitness.com/topics/depression) schizophrenia, and addiction to obesity and diabetes, and may serve as a hormone. It is perhaps best known for its influence on the formation, growth, survival, and development of neurons and for its role in mediating th...
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        [Topic] Berberine
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Background
Berberine is an alkaloid compound present in the roots, stems, rhizomes, and bark of a variety of plants, including Californian poppy, goldenseal, cork tree, Chinese goldthread, Oregon grape, and several plants in the Berberis genus. It is also widely available as a dietary supplement. Berberine has a long history of use in the ancient and traditional medicine systems of India, China, and Persia. Research demonstrates that berberine may exert pharmacological effects against certain chronic health conditions such as cardiovascular disease, gastrointestinal disor...
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          <span class="search-tag">diabetes</span>
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          <span class="search-tag">fatty liver</span>
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        [Topic] Zinc
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Background
Zinc is an essential nutrient that participates in numerous biological processes and modulates the activity of more than 300 enzymes and 2,000 transcription factors.[ref doi=&#39;10.1136/bmj.326.7386.409&#39;] First identified for its influence on growth and development, zinc is now understood to play critical roles in immune function, protein synthesis, wound healing, DNA synthesis, and cell division. 
History
The importance of zinc in the human diet first became apparent in the early 1960s, after a patient with a rare syndrome presented to Dr. Ananda Prasad, a physic...
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        [Topic] Sauna
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Bathing oneself in heat for the purposes of purification, cleansing, and healing is an ancient practice, dating back thousands of years and observed across many cultures. Variations of its use are seen today in the banyas of Russia, the sweat lodges of the American Indians, and, most famously, the saunas of Finland. 
Sauna use, sometimes referred to as &quot;sauna bathing,&quot; is characterized by short-term passive exposure to extreme heat. This exposure elicits mild hyperthermia – an increase in the body&#39;s core temperature – that induces a thermoregulatory response involving neu...
          <span class="search-tag">exercise</span>
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          <span class="search-tag">heat stress</span>
          <span class="search-tag">interesting</span>
          <span class="search-tag">alzheimer&#39;s</span>
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