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    <a data-turbo="false" href="/episodes/aliquot-133-creatine-brain">
      <h3 class="bold">
        [Podcast] Aliquot #133: The Surprising Effects of Creatine on the Brain
      </h3>
</a>    <p>
      Creatine plays a key role in maintaining cellular energy balance, and evidence suggests it can help the brain...
...
          <span class="search-tag">stress</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">concussion</span>
          <span class="search-tag">neurodegeneration</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">depression</span>
          <span class="search-tag">aliquot</span>
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      <h3 class="bold">
        [Podcast] Aliquot #131: The Muscle and Bone Benefits of Creatine
      </h3>
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      Creatine is one of the most widely studied and commonly used supplements in sports nutrition...
...
          <span class="search-tag">aliquot</span>
          <span class="search-tag">muscle</span>
          <span class="search-tag">supplements</span>
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    <a data-turbo="false" href="/episodes/creatine-aging-stressed-brains">
      <h3 class="bold">
        [Podcast] How Creatine Supports the Brain During Stress and Sleep Loss
      </h3>
</a>    <p>
      Drs. Rhonda Patrick and Darren Candow discuss creatine dosing for brain energy, aging, sleep loss, and mental fatigue.
...
          <span class="search-tag">brain</span>
          <span class="search-tag">sleep</span>
          <span class="search-tag">supplements</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">creatine</span>
          <span class="search-tag">cognition</span>
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      <h3 class="bold">
        [Podcast] How Creatine Supports Strength, Training, and Recovery
      </h3>
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      Drs. Rhonda Patrick and Darren Candow explain how creatine supports strength, training capacity, recovery, and muscle adaptation.
...
          <span class="search-tag">supplements</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">performance</span>
          <span class="search-tag">muscle</span>
          <span class="search-tag">strength</span>
          <span class="search-tag">creatine</span>
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    <a data-turbo="false" href="/episodes/aliquot-115-lifestyle-guide-mitochondria">
      <h3 class="bold">
        [Podcast] Aliquot #115: A Lifestyle Guide for Mitochondrial Optimization
      </h3>
</a>    <p>
      Mitochondrial health and overall health are intrinsically linked. Identifying ways to boost mitochondrial biogenesis...
...
          <span class="search-tag">aliquot</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">metabolism</span>
          <span class="search-tag">mitochondria</span>
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        [Topic] Microplastics
      </h3>
</a>    <p>
      [toc position=&#39;left&#39;]
Introduction
Microplastics are everywhere: in the food we eat, the water we drink, and even the air we breathe. Imagine consuming the equivalent of a credit card’s worth of plastic every week—just by going about your daily routine. As startling as it may seem, this is the reality we face, exposing our bodies to a hidden threat that’s growing by the day.
What are microplastics? They&#39;re tiny pieces of plastic or other polymer-based materials, ranging from 5 millimeters (~0.2 inches) to as small as 100 nanometers, often called nanoplastics. These tiny particles contain a var...
          <span class="search-tag">environment</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">cardiovascular</span>
          <span class="search-tag">Microplastics</span>
          <span class="search-tag">pollution</span>
          <span class="search-tag">PFAS</span>
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      <h3 class="bold">
        [Podcast] Dr. Peter Attia on Mastering Longevity – Insights on Cancer Prevention, Heart Disease, and Aging
      </h3>
</a>    <p>
      Dr. Peter Attia presents practical steps we can implement to improve our health, emphasizing the importance of each aspect while providing actionable advice. 
...
          <span class="search-tag">aging</span>
          <span class="search-tag">cancer</span>
          <span class="search-tag">metabolism</span>
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      <h3 class="bold">
        [Podcast] How Heat Therapy Improves Slow Wave Sleep
      </h3>
</a>    <p>
      Heat therapy (saunas, exercise, hot baths) can enhance slow-wave sleep. This video explores exercise and heat&#39;s joint role in sleep regulation.
...
          <span class="search-tag">sleep</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">hormones</span>
          <span class="search-tag">immune system</span>
          <span class="search-tag">coffee</span>
          <span class="search-tag">rhonda</span>
          <span class="search-tag">heat stress</span>
          <span class="search-tag">sauna</span>
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        [Topic] Senescence 
      </h3>
</a>    <p>
      [toc position=&#39;left&#39;]
Senescence is a response to stress in which damaged cells terminate normal growth cycles to prevent dysfunctional cells from reproducing. Senescence is a vital cellular process involved in embryonic development, wound healing, and cancer immunity; [ref doi=&#39;10.1242/dev.151837&#39;] however, the accumulation of senescent cells is associated with diseases of aging such as cancer, cardiovascular disease, type 2 diabetes, Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, sarcopenia, and glaucoma.[ref doi=&#39;10.1016/j.cell.2017.05.015&#39;] [ref doi=&#39;10.3390/ijms19102937&#39;] 
...
          <span class="search-tag">neurodegeneration</span>
          <span class="search-tag">senescence</span>
          <span class="search-tag">aging</span>
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      <h3 class="bold">
        [Story] Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting &amp; Protein Acetylation
      </h3>
</a>    <p>
      TIMELINE:
00:03:22 (https://www.youtube.com/watch?v=Gm626MgpveI&amp;amp;t=00h03m22s) - How genetically inhibiting autophagy actually increases cellular sensitivity to death and how this was counterintuitive because autophagy was thought, at one time, as a type of activity predominantly concerned with actually initiating cell death.
00:04:44 (https://www.youtube.com/watch?v=Gm626MgpveI&amp;amp;t=00h04m44s) - The external signals causing autophagy.
00:05:29 (https://www.youtube.com/watch?v=Gm626MgpveI&amp;amp;t=00h05m29s) - The role of growth factors in transporting nutrients from the outside world into the...
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