Dr. Rhonda Patrick and Dr. Steve Horvath discuss how epigenetic clocks measure biological age and which proven interventions actually slow or reverse aging. ... epigenetics telomeres genetics stem cells omega-3 dna damage biomarkers aging vitamin d senescence multivitamin
Watch nowCardiovascular disease is the leading cause of death in the United States, but men and women do not develop it on the same timeline. To identify when these differences begin, researchers followed a large group of adults from young adulthood into midlife and recorded when their first cardiovascular events occurred. The analysis used data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, which enrolled 5,115 adults aged 18 to 30 in the mid-1980s and followed them for more than 30 years. Researchers compared men and women to determine when "premature" cardiovascular disea... aging cardiovascular
Read moreDr. Rhonda Patrick discusses fragmented sleep, lipid biomarkers including ApoB and LP(a), coffee makers and bean quality, and choline supplementation. ... biomarkers heart disease coffee sauna supplements sleep rhonda Microplastics Ubiquinol magnesium L-Theanine
Watch nowDr. Levine details his research findings that show how a structured exercise regimen can reverse up to 20 years of heart aging. ... exercise aging cardiovascular
Watch nowVitamin D protects pancreatic beta cells in type 2 diabetes. Chronic inflammation is a principal driver of many of the pathological processes that accompany type 2 diabetes, a metabolic disorder characterized by hyperglycemia (high blood glucose) and subsequent pancreatic beta cell dysfunction. Findings from a recent study suggest that vitamin D blocks activation of the NLRP3 inflammasome, preventing inflammation-driven impairment of pancreatic beta cells. The NLRP3 inflammasome is a large, intracellular complex that plays critical roles in immune function. Its activation triggers the relea... vitamin d insulin
Read moreAging causes brain changes that impair cognitive function, even in people who do not have Alzheimer’s disease or dementia. However, lifestyle factors like diet and exercise have significant influence over the rate of cognitive decline. Previous research has shown that exercise improves brain health and cognitive function during aging. A new report details the role of the muscle hormone irisin in the neuroprotective effects of exercise Irisin, a type of myokine, is a hormone secreted from muscle in response to exercise. Previous research has shown that irisin may mediate some of the beneficial ... exercise brain alzheimer's aging hormones neurodegeneration
Read moreOpioid use disorder is defined as a problematic pattern of opioid use that leads to serious impairment or distress. It has emerged as a public health crisis in the United States, affecting as many as two million people aged 12 years and older. A multifaceted approach to reducing opioid use disorders involves targeting preventable environmental factors in addition to restricting opioid prescriptions. One group of researchers investigated the effects of vitamin D status on reward-seeking behaviors like opioid use and sunlight exposure in mice. Opioid drugs are highly addictive due to their effe... vitamin d addiction
Read moreCOVID-19 Q&A Part 2: Rhonda Patrick, Ph.D. answers subscriber questions in a multi-part series. ... covid-19 vitamin d nutrition exercise microbiome sleep vitamin c omega-3 inflammation immune system virus micronutrients vitamin e vaccine genetics testosterone estrogen zinc fiber autoimmunity
Watch nowDr. Dale Bredesen discusses treatments that may reverse symptoms of mild cognitive decline and Alzheimer’s disease. ... alzheimer's brain diet aging hormones insulin resistance inflammation dementia insulin
Watch nowFasting or beta-hydroxybutyrate administration reduces cellular senescence. Beta-hydroxybutyrate (BHB) (https://foundmyfitness.com/topics/beta-hydroxybutyrate) is a ketone produced by the body during times of carbohydrate scarcity such as those encountered while practicing a ketogenic diet (https://www.sciencedirect.com/science/article/pii/S1550413117304904), fasting (https://www.mdpi.com/2072-6643/12/4/1194), or exercise (https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2707428), which have all demonstrated the ability to extend healthspan and lifespan. However, the precise effect... aging ketosis heart disease dna damage fasting ketogenic diet
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